Title : Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.

Pub. Date : 2009 Sep

PMID : 20196786






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SHP1 expression correlates with down-regulation of Janus kinase/signal transducers and activators of transcription (JAK2/STAT3/STAT5) signalling, which is mediated in part by tyrosine dephosphorylation events and modulation of the proteasome pathway. Tyrosine protein tyrosine phosphatase non-receptor type 6 Homo sapiens