Pub. Date : 2007 Jan
PMID : 17404032
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, SHP-1 translocation from cytosol to membrane is not affected by band 3 P-Tyr level, because it is not mediated by the SH2-P-Tyr recruitment mechanism, and localizes into the cytoskeletal compartment. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |
| 2 | Band 3 is the target of SHP-1, which dephosphorylates Tyr 8, 21, and 904. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |
| 3 | We hypothesize that the presence of both SHP-2 and SHP-1 ensures band 3 dephosphorylation in different conditions: SHP-2, through interaction of its SH2 domain/s to P-Tyr protein, is regulated by the band 3 Tyr-phosphorylation level; SHP-1 may be involved by simple membrane rearrangement. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |
| 4 | We hypothesize that the presence of both SHP-2 and SHP-1 ensures band 3 dephosphorylation in different conditions: SHP-2, through interaction of its SH2 domain/s to P-Tyr protein, is regulated by the band 3 Tyr-phosphorylation level; SHP-1 may be involved by simple membrane rearrangement. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |