| 1 |
34140545 | Concomitant attenuation of HMGCR expression and activity enhances the growth inhibitory effect of atorvastatin on TGF-β-treated epithelial cancer cells. | 2021 Jun 17 |
3 |
| 2 |
32523820 | Statin-Induced Immune-Mediated Necrotizing Myopathy: An Increasingly Recognized Inflammatory Myopathy. | 2020 May 5 |
1 |
| 3 |
33027917 | The Association of 3-Hydroxy-3-Methylglutaryl-CoA Reductase, Apolipoprotein E, and Solute Carrier Organic Anion Genetic Variants with Atorvastatin Response among Jordanian Patients with Type 2 Diabetes. | 2020 Oct 5 |
1 |
| 4 |
31005367 | Targeted delivery of atorvastatin via asialoglycoprotein receptor (ASGPR). | 2019 Jun 1 |
1 |
| 5 |
31253872 | Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. | 2019 Jul |
1 |
| 6 |
31423616 | Atorvastatin induces mitochondrial dysfunction and cell apoptosis in HepG2 cells via inhibition of the Nrf2 pathway. | 2019 Oct |
2 |
| 7 |
31450089 | Simultaneous analysis of the total plasma concentration of atorvastatin and its five metabolites and the unbound plasma concentration of atorvastatin: Application in a clinical pharmacokinetic study of single oral dose. | 2019 Sep 15 |
2 |
| 8 |
28802579 | Atorvastatin prevents endothelial dysfunction in high glucose condition through Skp2-mediated degradation of FOXO1 and ICAM-1. | 2018 Jan 8 |
1 |
| 9 |
29427701 | Statins differentially modulate microRNAs expression in peripheral cells of hyperlipidemic subjects: A pilot study. | 2018 May 30 |
1 |
| 10 |
29615666 | Insensitivity to atorvastatin is associated with increased accumulation of intracellular lipid droplets and fatty acid metabolism in breast cancer cells. | 2018 Apr 3 |
1 |
| 11 |
30034619 | Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics. | 2018 Jun 29 |
2 |
| 12 |
30595323 | Randomized controlled trial comparing the efficacy of daily and every other day atorvastatin therapy and its correlation with serum hydroxymethylglutaryl-CoA reductase enzyme levels in naïve dyslipidemic patients. | 2018 Dec |
1 |
| 13 |
27738832 | Effects of Topical Atorvastatin (2 %) on Posthemorrhoidectomy Pain and Wound Healing: A Randomized Double-Blind Placebo-Controlled Clinical Trial. | 2017 Feb |
1 |
| 14 |
28745862 | GlcNAc Conjugated Atorvastatin with Enhanced Water Solubility and Cellular Internalization. | 2017 Aug 16 |
1 |
| 15 |
29065216 | Inhibition of Cholesterol Synthesis in HepG2 Cells by GINST-Decreasing HMG-CoA Reductase Expression Via AMP-Activated Protein Kinase. | 2017 Nov |
1 |
| 16 |
29441875 | Influence of SLCO1B1 polymorphisms on atorvastatin efficacy and safety in Macedonian subjects. | 2017 May 1 |
1 |
| 17 |
26408409 | HMGCR rs17671591 SNP Determines Lower Plasma LDL-C after Atorvastatin Therapy in Chilean Individuals. | 2016 Apr |
3 |
| 18 |
26886305 | Pharmaceutical Applications of Relaxation Filter-Selective Signal Excitation Methods for ¹⁹F Solid-State Nuclear Magnetic Resonance: Case Study With Atorvastatin in Dosage Formulation. | 2016 Mar |
2 |
| 19 |
26908399 | Varicose Remodeling of Veins Is Suppressed by 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors. | 2016 Feb 23 |
1 |
| 20 |
25591572 | Use of atorvastatin in lipid disorders and cardiovascular disease in Chinese patients. | 2015 Jan 20 |
1 |
| 21 |
25668447 | Systematic investigation of cellular response and pleiotropic effects in atorvastatin-treated liver cells by MS-based proteomics. | 2015 Mar 6 |
1 |
| 22 |
25745361 | PBK/TOPK mediates geranylgeranylation signaling for breast cancer cell proliferation. | 2015 |
2 |
| 23 |
26091578 | Expression of OATP2B1 as determinant of drug effects in the microcompartment of the coronary artery. | 2015 Sep |
1 |
| 24 |
24232833 | Chemical and enzymatic approaches to the synthesis of optically pure ethyl (R)-4-cyano-3-hydroxybutanoate. | 2014 Jan |
2 |
| 25 |
24233489 | Inflammatory stress induces statin resistance by disrupting 3-hydroxy-3-methylglutaryl-CoA reductase feedback regulation. | 2014 Feb |
2 |
| 26 |
24575888 | Asymmetric synthesis of the HMG-CoA reductase inhibitor atorvastatin calcium: an organocatalytic anhydride desymmetrization and cyanide-free side chain elongation approach. | 2014 Mar 21 |
1 |
| 27 |
24783072 | Alternate Day versus Once Daily Atorvastatin for Primary Prevention of (CHD) in Naïve Patients of Dyslipidemia. | 2014 Mar |
1 |
| 28 |
24895437 | Inflammatory stress reduces the effectiveness of statins in the kidney by disrupting HMGCoA reductase feedback regulation. | 2014 Oct |
3 |
| 29 |
24932497 | Stimulatory interactions between human coronary smooth muscle cells and dendritic cells. | 2014 |
1 |
| 30 |
25013913 | Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase. | 2014 |
1 |
| 31 |
25022881 | Molecular modeling studies of atorvastatin analogues as HMGR inhibitors using 3D-QSAR, molecular docking and molecular dynamics simulations. | 2014 Aug 15 |
1 |
| 32 |
25311809 | Inhibition of protein geranylgeranylation specifically interferes with CD40-dependent B cell activation, resulting in a reduced capacity to induce T cell immunity. | 2014 Nov 15 |
1 |
| 33 |
23471651 | Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial. | 2013 Apr |
2 |
| 34 |
24177008 | Atorvastatin inhibited Rho-associated kinase 1 (ROCK1) and focal adhesion kinase (FAK) mediated adhesion and differentiation of CD133+CD44+ prostate cancer stem cells. | 2013 Nov 22 |
1 |
| 35 |
21427285 | Effect of HMGCR variant alleles on low-density lipoprotein cholesterol-lowering response to atorvastatin in healthy Korean subjects. | 2012 Mar |
3 |
| 36 |
22108629 | Rationale and design of a trial on the effect of high dose statins on cardiovascular risk in adults after successful coarctation repair. | 2012 Mar |
1 |
| 37 |
22177940 | Explication of interactions between HMGCR isoform 2 and various statins through In silico modeling and docking. | 2012 Feb |
1 |
| 38 |
22569288 | Comparison of alternate-day atorvastatin treatment to daily treatment in maintaining LDL-cholesterol targets in patients with variable coronary risk profile. | 2012 May |
1 |
| 39 |
22989091 | A novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) splice variant with an alternative exon 1 potentially encoding an extended N-terminus. | 2012 Sep 18 |
2 |
| 40 |
23525139 | ChemVassa: A New Method for Identifying Small Molecule Hits in Drug Discovery. | 2012 |
1 |
| 41 |
21083855 | Effects of high-dose statin on the human hepatic expression of genes involved in carbohydrate and triglyceride metabolism. | 2011 Mar |
1 |
| 42 |
21123766 | Atorvastatin increases intestinal expression of NPC1L1 in hyperlipidemic men. | 2011 Mar |
3 |
| 43 |
21871913 | Antinociception induced by atorvastatin in different pain models. | 2011 Nov |
1 |
| 44 |
19930424 | Atorvastatin increases expression of low-density lipoprotein receptor mRNA in human circulating mononuclear cells. | 2010 Apr |
1 |
| 45 |
20108992 | Amlodipine/Atorvastatin: a review of its use in the treatment of hypertension and dyslipidaemia and the prevention of cardiovascular disease. | 2010 |
2 |
| 46 |
20177788 | Combined hyperlipidemia in patients with lysinuric protein intolerance. | 2010 Dec |
1 |
| 47 |
20387911 | Does a single-pill antihypertensive/lipid-lowering regimen improve adherence in US managed care enrolees? A non-randomized, observational, retrospective study. | 2010 |
1 |
| 48 |
20578904 | Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy. | 2010 Oct |
2 |
| 49 |
20653359 | Effects of lipid-lowering therapy on reduction of cardiovascular events in patients with end-stage renal disease requiring hemodialysis. | 2010 Aug |
1 |
| 50 |
20678686 | Pharmacokinetics and bioequivalence evaluation of two different atorvastatin calcium 10-mg tablets: A single-dose, randomized-sequence, open-label, two-period crossover study in healthy fasted Chinese adult males. | 2010 Jul |
1 |