Pub. Date : 2016 Apr
PMID : 26408409
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | HMGCR rs17671591 SNP Determines Lower Plasma LDL-C after Atorvastatin Therapy in Chilean Individuals. | Atorvastatin | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |
| 2 | Hence, we aimed to evaluate the contribution of PCSK9 rs7552841 and HMGCR rs17671591 SNPs as genetic determinants of atorvastatin response in Chilean hypercholesterolaemic individuals. | Atorvastatin | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |
| 3 | Our data suggest that the HMGCR rs17671591 polymorphism can constitute a genetic marker of lower plasma LDL-C and enhanced HDL-C concentration after atorvastatin therapy in the Chilean population. | Atorvastatin | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |