Title : A novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) splice variant with an alternative exon 1 potentially encoding an extended N-terminus.

Pub. Date : 2012 Sep 18

PMID : 22989091






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Atorvastatin treatment of HepG2 cells resulted in increased HMGCR-1b mRNA levels, but unaltered proximal promoter activity compared to untreated cells. Atorvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
2 In contrast, HMGCR-1c showed a more restricted transcription pattern, but was also induced by atorvastatin treatment. Atorvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens