Title : Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase.

Pub. Date : 2014

PMID : 25013913






1 Functional Relationships(s)
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1 Previously we could induce T cell tolerance by applying a 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitor (HMGCRI) atorvastatin, which also modulates MHC class II expression and has therapeutic potential in autoimmune disease. Atorvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens