retinoid X receptor alpha ; Homo sapiens






1517 Article(s)
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1451 33246082 Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population. Infect Genet Evol 2021 Jan 1
1452 33300271 Effects of maternal and fetal choline concentrations on the fetal growth and placental DNA methylation of 12 target genes related to fetal growth, adipogenesis, and energy metabolism. J Obstet Gynaecol Res 2021 Feb 3
1453 33378197 Convenient Retinoid X Receptor Binding Assay Based on Fluorescence Change of the Antagonist NEt-C343. J Med Chem 2021 Jan 14 3
1454 33453499 L-carnitine exerts a nutrigenomic effect via direct modulation of nuclear receptor signaling in adipocytes, hepatocytes and SKMC, demonstrating its nutritional impact. Nutr Res 2021 Jan 1
1455 33472949 Cross-talk between YAP and RAR-RXR Drives Expression of Stemness Genes to Promote 5-FU Resistance and Self-Renewal in Colorectal Cancer Cells. Mol Cancer Res 2021 Apr 2
1456 33497820 The role of the retinoid receptor, RAR/RXR heterodimer, in liver physiology. Biochim Biophys Acta Mol Basis Dis 2021 May 1 2
1457 33499199 Retinoid Regulation of Ocular Surface Innate Inflammation. Int J Mol Sci 2021 Jan 22 1
1458 33527324 RXR Negatively Regulates Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem and Progenitor Cells. Stem Cell Rev Rep 2021 Aug 2
1459 33570383 Evaluating Novel RXR Agonists That Induce ApoE and Tyrosine Hydroxylase in Cultured Human Glioblastoma Cells. ACS Chem Neurosci 2021 Mar 3 2
1460 33572750 Reorganization of Metabolism during Cardiomyogenesis Implies Time-Specific Signaling Pathway Regulation. Int J Mol Sci 2021 Jan 29 2
1461 33581653 Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2. Biomed Pharmacother 2021 May 3
1462 33599853 Bexarotene inhibits cell proliferation by inducing oxidative stress, DNA damage and apoptosis via PPARγ/ NF-κB signaling pathway in C6 glioma cells. Med Oncol 2021 Feb 18 1
1463 33708882 Comparative proteomics analysis for identifying the lipid metabolism related pathways in patients with Klippel-Feil syndrome. Ann Transl Med 2021 Feb 2
1464 33745150 Genome-wide association study of stage III/IV grade C periodontitis (former aggressive periodontitis) in a Spanish population. J Clin Periodontol 2021 Jul 1
1465 33749892 ω3 fatty acid metabolite, 12-hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor α. FASEB J 2021 Apr 3
1466 33793232 Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics. J Med Chem 2021 Apr 22 3
1467 33809241 Vitamin A5/X, a New Food to Lipid Hormone Concept for a Nutritional Ligand to Control RXR-Mediated Signaling. Nutrients 2021 Mar 12 3
1468 33809931 DHA and Its Metabolites Have a Protective Role against Methylmercury-Induced Neurotoxicity in Mouse Primary Neuron and SH-SY5Y Cells. Int J Mol Sci 2021 Mar 22 6
1469 33832420 CRABP1 and CRABP2 Protein Levels Correlate with Each Other but Do Not Correlate with Sensitivity of Breast Cancer Cells to Retinoic Acid. Biochemistry (Mosc) 2021 Feb 2
1470 33878891 A regulative epigenetic circuit supervised by HDAC7 represses IGFBP6 and IGFBP7 expression to sustain mammary stemness. Epigenomics 2021 May 2
1471 34002323 Modulation of lung cytoskeletal remodeling, RXR based metabolic cascades and inflammation to achieve redox homeostasis during extended exposures to lowered pO<sub>2</sub>. Apoptosis 2021 Aug 1
1472 34023650 Discovery of new chalone adamantyl arotinoids having RXRα-modulating and anticancer activities. Bioorg Chem 2021 Aug 3
1473 34057057 Mechanistic aspects of carotenoid health benefits - where are we now? Nutr Res Rev 2021 Dec 1
1474 34081964 Heterodimer formation with retinoic acid receptor RXRα modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARγ. J Biol Chem 2021 Jul 5
1475 34087410 Calcitriol and Retinoic acid antagonize each other to suppress the production of IL-9 by Th9 cells. J Nutr Biochem 2021 Oct 6
1476 34091780 Role of Vitamin D deficiency and mRNA expression of VDR and RXR in haematological cancers. Mol Biol Rep 2021 May 1
1477 34134472 RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells. Haematologica 2022 Feb 1 3
1478 34141088 Creation of Fluorescent RXR Antagonists Based on CBTF-EE and Application to a Fluorescence Polarization Binding Assay. ACS Med Chem Lett 2021 Jun 10 2
1479 34142331 Pharmacological Activation of RXR-α Promotes Hematoma Absorption via a PPAR-γ-dependent Pathway After Intracerebral Hemorrhage. Neurosci Bull 2021 Oct 3
1480 34157397 Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor α-mediated β-galactoside α2,6-sialyltransferase I expression in human hepatocarcinoma cells. Int J Biochem Cell Biol 2021 Aug 1
1481 34224682 Retinoids promote penis development in sequentially hermaphroditic snails. Dev Biol 2021 Oct 2
1482 34296739 Ligands and DNA in the allosteric control of retinoid receptors function. Essays Biochem 2021 Dec 17 4
1483 34298684 The BET Inhibitor JQ1 Augments the Antitumor Efficacy of Gemcitabine in Preclinical Models of Pancreatic Cancer. Cancers (Basel) 2021 Jul 11 2
1484 34298981 PPARdelta in Affected Atopic Dermatitis and Psoriasis: A Possible Role in Metabolic Reprograming. Int J Mol Sci 2021 Jul 8 1
1485 34299349 Retinoids as Chemo-Preventive and Molecular-Targeted Anti-Cancer Therapies. Int J Mol Sci 2021 Jul 20 2
1486 34303232 An ancestral nuclear receptor couple, PPAR-RXR, is exploited by organotins. Sci Total Environ 2021 Nov 25 3
1487 34312718 Prospecting the therapeutic edge of a novel compound (B12) over berberine in the selective targeting of Retinoid X Receptor in colon cancer. J Mol Model 2021 Jul 26 13
1488 34385920 Antiatherogenic Effects of Quercetin in the THP-1 Macrophage Model <i>In Vitro</i>, With Insights Into Its Signaling Mechanisms Using <i>In Silico</i> Analysis. Front Pharmacol 2021 2
1489 34445672 Mechanisms Mediating the Regulation of Peroxisomal Fatty Acid Beta-Oxidation by PPARα. Int J Mol Sci 2021 Aug 20 2
1490 34447379 The MS Remyelinating Drug Bexarotene (an RXR Agonist) Promotes Induction of Human Tregs and Suppresses Th17 Differentiation <i>In Vitro</i>. Front Immunol 2021 4
1491 34484127 A Review of Human Exposure to Microplastics and Insights Into Microplastics as Obesogens. Front Endocrinol (Lausanne) 2021 6
1492 34502180 Activation of the Constitutive Androstane Receptor Inhibits Leukocyte Adhesiveness to Dysfunctional Endothelium. Int J Mol Sci 2021 Aug 27 2
1493 34509914 Chemoproteomic profiling reveals cellular targets of nitro-fatty acids. Redox Biol 2021 Oct 2
1494 34539418 α-Mangostin Induces Apoptosis and Inhibits Metastasis of Breast Cancer Cells via Regulating RXRα-AKT Signaling Pathway. Front Pharmacol 2021 4
1495 34544906 A2E-induced inflammation and angiogenesis in RPE cells <i>in vitro</i> are modulated by PPAR-α, -β/δ, -γ, and RXR antagonists and by norbixin. Aging (Albany NY) 2021 Sep 20 3
1496 34562448 Vitamin D signaling inhibits HBV activity by directly targeting the HBV core promoter. J Biol Chem 2021 Oct 2
1497 34603059 Multi-Omics Approach to Dissect the Mechanisms of Rexinoid Signaling in Myoblast Differentiation. Front Pharmacol 2021 2
1498 34638488 The RXR Agonist MSU42011 Is Effective for the Treatment of Preclinical HER2+ Breast Cancer and Kras-Driven Lung Cancer. Cancers (Basel) 2021 Oct 6 3
1499 34725922 Non-genomic rewiring of vitamin D receptor to p53 as a key to Alzheimer's disease. Aging Cell 2021 Dec 2
1500 34782454 Desmosterol suppresses macrophage inflammasome activation and protects against vascular inflammation and atherosclerosis. Proc Natl Acad Sci U S A 2021 Nov 23 2