Pub. Date : 2021 Sep 20
PMID : 34544906
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A2E-induced inflammation and angiogenesis in RPE cells in vitro are modulated by PPAR-alpha, -beta/delta, -gamma, and RXR antagonists and by norbixin. | N-retinylidene-N-retinylethanolamine | retinoid X receptor alpha | Homo sapiens |
| 2 | Norbixin inhibits PPAR and RXR transactivation induced by A2E. | norbixin | retinoid X receptor alpha | Homo sapiens |
| 3 | In addition, a cocktail of all three PPARs antagonists and also HX531, an antagonist of RXR reproduce norbixin effects on inflammation. | norbixin | retinoid X receptor alpha | Homo sapiens |