Title : RXR Negatively Regulates Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem and Progenitor Cells.

Pub. Date : 2021 Aug

PMID : 33527324






2 Functional Relationships(s)
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1 RXR agonist Bexarotene notably suppressed ex vivo expansion of CB HSCs. Bexarotene retinoid X receptor alpha Homo sapiens
2 Activation of RXR by Bexarotene significantly blocked expansion of phenotypic HSCs and HPCs and expressed increased functional HPCs as assessed by colony formation induced by UM171 and SR1. Bexarotene retinoid X receptor alpha Homo sapiens