Title : Mechanistic aspects of carotenoid health benefits - where are we now?

Pub. Date : 2021 Dec

PMID : 34057057






1 Functional Relationships(s)
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1 Antioxidant mechanisms - direct or via transcription factors such as NRF2 and NF-kappaB - and activation of nuclear hormone receptor pathways such as of RAR/RXR or also PPARs, via carotenoid-metabolites, are the basic principles which we try to connect with carotenoid-transmitted health benefits as exemplified with described common diseases including obesity/diabetes and cancer. Carotenoids retinoid X receptor alpha Homo sapiens