| 1 |
35197970 | Rapamycin Attenuated Zinc-Induced Tau Phosphorylation and Oxidative Stress in Rats: Involvement of Dual mTOR/p70S6K and Nrf2/HO-1 Pathways. | 2022 |
3 |
| 2 |
34034560 | The p70S6K/PI3K/MAPK feedback loop releases the inhibition effect of high-dose rapamycin on rat mesangial cell proliferation. | 2021 Jan-Dec |
5 |
| 3 |
34102263 | Rapamycin Accelerates Axon Regeneration Through Schwann Cell-mediated Autophagy Following Inferior Alveolar Nerve Transection in Rats. | 2021 Aug 1 |
1 |
| 4 |
34494222 | Insulin growth factor-1 enhances proliferation and inhibits apoptosis of neural progenitor cells by phosphorylation of Akt/mTOR/p70S6K molecules and triggering intrinsic apoptosis signaling pathway. | 2021 Sep 7 |
1 |
| 5 |
31782272 | Roles of the mammalian target of rapamycin (mTOR) signaling pathway in the repair of hyperoxia-induced acute lung injury. | 2020 Jan |
1 |
| 6 |
32642911 | Rapamycin Alleviates Hypertriglyceridemia-Related Acute Pancreatitis via Restoring Autophagy Flux and Inhibiting Endoplasmic Reticulum Stress. | 2020 Aug |
1 |
| 7 |
32660632 | Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organization in stress-induced senescence of MSCs. | 2020 Jul 13 |
1 |
| 8 |
32798557 | Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway. | 2020 Oct 15 |
4 |
| 9 |
33312358 | β-ecdysterone alleviates osteoarthritis by activating autophagy in chondrocytes through regulating PI3K/AKT/mTOR signal pathway. | 2020 |
1 |
| 10 |
30705972 | Selective androgen receptor modulator, S42 has anabolic and anti-catabolic effects on cultured myotubes. | 2019 Mar |
2 |
| 11 |
31057050 | The protective effect and mechanism of rapamycin in the rat model of IgA nephropathy. | 2019 Nov |
2 |
| 12 |
31152486 | Inhibition of the mTOR pathway: A new mechanism of β cell toxicity induced by tacrolimus. | 2019 Dec |
1 |
| 13 |
31518555 | Elevated p70S6K phosphorylation in rat soleus muscle during the early stage of unloading: Causes and consequences. | 2019 Oct 15 |
1 |
| 14 |
26911848 | Concomitant use of rapamycin and rosiglitazone delays the progression of polycystic kidney disease in Han:SPRD rats: a study of the mechanism of action. | 2018 May 1 |
1 |
| 15 |
29444470 | Effect of sirolimus on liver cirrhosis and hepatic encephalopathy of common bile duct-ligated rats. | 2018 Apr 5 |
1 |
| 16 |
29757673 | Rapamycin-insensitive mechanistic target of rapamycin regulates basal and resistance exercise-induced muscle protein synthesis. | 2018 May 14 |
1 |
| 17 |
30200803 | The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathway. | 2018 Nov |
2 |
| 18 |
30224017 | Rapamycin Supplementation May Ameliorate Erectile Function in Rats With Streptozotocin-Induced Type 1 Diabetes by Inducing Autophagy and Inhibiting Apoptosis, Endothelial Dysfunction, and Corporal Fibrosis. | 2018 Sep |
1 |
| 19 |
27827806 | Citrulline directly modulates muscle protein synthesis via the PI3K/MAPK/4E-BP1 pathway in a malnourished state: evidence from in vivo, ex vivo, and in vitro studies. | 2017 Jan 1 |
1 |
| 20 |
29240812 | Effects of vaspin on pancreatic β cell secretion via PI3K/Akt and NF-κB signaling pathways. | 2017 |
1 |
| 21 |
26374551 | Activation of mTOR signaling mediates the increased expression of AChE in high glucose condition: in vitro and in vivo evidences. | 2016 Sep |
1 |
| 22 |
27113190 | [Effect of rapamycin on proliferation of rat heart valve interstitial cells in vitro]. | 2016 Apr |
2 |
| 23 |
27371338 | Protective effects of PF-4708671 against N-methyl-d-aspartic acid-induced retinal damage in rats. | 2016 Dec |
1 |
| 24 |
27489506 | Rapamycin Reduced Ischemic Brain Damage in Diabetic Animals Is Associated with Suppressions of mTOR and ERK1/2 Signaling. | 2016 |
1 |
| 25 |
26048361 | Restoration of Normal Cerebral Oxygen Consumption with Rapamycin Treatment in a Rat Model of Autism-Tuberous Sclerosis. | 2015 Sep |
1 |
| 26 |
26297427 | The Akt/mTOR/p70S6K pathway is activated in IgA nephropathy and rapamycin may represent a viable treatment option. | 2015 Dec |
2 |
| 27 |
26770910 | The Effect of L-Ornithine on the Phosphorylation of mTORC1 Downstream Targets in Rat Liver. | 2015 Dec |
1 |
| 28 |
24375611 | Simvastatin promotes cardiac microvascular endothelial cells proliferation, migration and survival by phosphorylation of p70 S6K and FoxO3a. | 2014 May |
2 |
| 29 |
24404143 | Rapamycin ameliorates inflammation and fibrosis in the early phase of cirrhotic portal hypertension in rats through inhibition of mTORC1 but not mTORC2. | 2014 |
1 |
| 30 |
24586612 | Periadventitial application of rapamycin-loaded nanoparticles produces sustained inhibition of vascular restenosis. | 2014 |
2 |
| 31 |
22684415 | Rapamycin inhibits the mTOR/p70S6K pathway and attenuates cardiac fibrosis in adriamycin-induced dilated cardiomyopathy. | 2013 Apr |
2 |
| 32 |
23265586 | Enhanced expression of glucose transporter-1 in vascular smooth muscle cells via the Akt/tuberous sclerosis complex subunit 2 (TSC2)/mammalian target of rapamycin (mTOR)/ribosomal S6 protein kinase (S6K) pathway in experimental renal failure. | 2013 Feb |
1 |
| 33 |
23334408 | CL316,243, a selective β3-adrenoceptor agonist, activates protein translation through mTOR/p70S6K signaling pathway in rat skeletal muscle cells. | 2013 Apr |
1 |
| 34 |
23470622 | Rapamycin reverses pulmonary artery smooth muscle cell proliferation in pulmonary hypertension. | 2013 May |
3 |
| 35 |
23566837 | Rapamycin preserves the follicle pool reserve and prolongs the ovarian lifespan of female rats via modulating mTOR activation and sirtuin expression. | 2013 Jul 1 |
1 |
| 36 |
23635649 | Isoflurane preconditioning increases survival of rat skin random-pattern flaps by induction of HIF-1α expression. | 2013 |
1 |
| 37 |
23994018 | Ghrelin-induced food intake and adiposity depend on central mTORC1/S6K1 signaling. | 2013 Dec 5 |
1 |
| 38 |
24116273 | Destabilization of TNF-α mRNA by Rapamycin. | 2012 Jan |
1 |
| 39 |
21544240 | Hyperactive S6K1 mediates oxidative stress and endothelial dysfunction in aging: inhibition by resveratrol. | 2011 Apr 22 |
1 |
| 40 |
22067655 | Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation? | 2011 Oct 15 |
1 |
| 41 |
20299475 | Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue. | 2010 Jun |
1 |
| 42 |
20517583 | mTOR regulates the invasive properties of synovial fibroblasts in rheumatoid arthritis. | 2010 Sep-Oct |
1 |
| 43 |
20678995 | ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats. | 2010 Sep 1 |
1 |
| 44 |
19526041 | Infarct size is increased in female post-MI rats treated with rapamycin. | 2009 Jun |
1 |
| 45 |
19589861 | Mammalian target of rapamycin is activated in association with myometrial proliferation during pregnancy. | 2009 Oct |
1 |
| 46 |
19622787 | The effects of amino acids on glucose metabolism of isolated rat skeletal muscle are independent of insulin and the mTOR/S6K pathway. | 2009 Sep |
1 |
| 47 |
18094073 | Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation. | 2008 Mar |
2 |
| 48 |
18776140 | Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system. | 2008 Dec |
1 |
| 49 |
17135708 | Vasopressin stimulates Na-dependent phosphate transport and calcification in rat aortic smooth muscle cells. | 2007 Feb |
1 |
| 50 |
17389711 | Rapamycin blunts nutrient stimulation of eIF4G, but not PKCepsilon phosphorylation, in skeletal muscle. | 2007 Jul |
1 |