Title : Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organization in stress-induced senescence of MSCs.

Pub. Date : 2020 Jul 13

PMID : 32660632






1 Functional Relationships(s)
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1 Suppression of mTORC1/p70S6K pathway by either rapamycin or p70S6K knockdown promoted heterochromatin organization and ameliorated Dox- or H2O2-induced DNA damage and senescence. Sirolimus ribosomal protein S6 kinase B1 Rattus norvegicus