Title : Destabilization of TNF-α mRNA by Rapamycin.

Pub. Date : 2012 Jan

PMID : 24116273






1 Functional Relationships(s)
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1 The antigen-induced activation of S6K1 is inhibited by specific kinase inhibitors including mTOR, PI3K, PKC and Ca(2+)chelator inhibitor, while TNF-alpha mRNA level is reduced only by rapamycin treatment. Sirolimus ribosomal protein S6 kinase B1 Rattus norvegicus