Doxorubicin

cyclin dependent kinase 1 ; Homo sapiens







19 Article(s)
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1 25683911 Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells. 2015 May 2
2 25149538 ╬▓TrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy. 2014 Sep 15 1
3 25217394 The cell death and DNA damages caused by the Tet-On regulating HSV-tk/GCV suicide gene system in MCF-7 cells. 2014 Sep 1
4 23343191 Potentiation of in vitro and in vivo antitumor efficacy of doxorubicin by cyclin-dependent kinase inhibitor P276-00 in human non-small cell lung cancer cells. 2013 Jan 23 4
5 22536785 Melatonin suppresses doxorubicin-induced premature senescence of A549 lung cancer cells by ameliorating mitochondrial dysfunction. 2012 Nov 1
6 22580740 Pirarubicin inhibits multidrug-resistant osteosarcoma cell proliferation through induction of G2/M phase cell cycle arrest. 2012 Jun 1
7 21539811 Nek6 suppresses the premature senescence of human cancer cells induced by camptothecin and doxorubicin treatment. 2011 May 20 2
8 20112430 A novel calmodulin antagonist O-(4-ethoxyl-butyl)-berbamine overcomes multidrug resistance in drug-resistant MCF-7/ADR breast carcinoma cells. 2010 Jul 1
9 19185564 Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin. 2009 Apr 1 5
10 19375851 Increased expression of cdc2 inhibits transport function of RLIP76 and promotes apoptosis. 2009 Oct 8 3
11 17869387 Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases. 2008 Jun 4
12 16807237 DNA damage-induced down-regulation of human Cdc25C and Cdc2 is mediated by cooperation between p53 and maintenance DNA (cytosine-5) methyltransferase 1. 2006 Aug 25 3
13 16036217 Cdc2 and Cdk2 play critical roles in low dose doxorubicin-induced cell death through mitotic catastrophe but not in high dose doxorubicin-induced apoptosis. 2005 Sep 9 6
14 15141020 Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms. 2004 May 1
15 15257900 [Effect of XK469 and adriamycin on the growth of H460 cells in vitro and its mechanism]. 2004 Jul 3
16 12676925 Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents. 2003 Jun 13 2
17 11096075 NF-Y mediates the transcriptional inhibition of the cyclin B1, cyclin B2, and cdc25C promoters upon induced G2 arrest. 2001 Feb 23 1
18 11329882 Inhibition of X-ray and doxorubicin-induced apoptosis by butyrolactone I, a CDK-specific inhibitor, in human tumor cells. 2000 Dec 1
19 10454534 The G(2) checkpoint is maintained by redundant pathways. 1999 Sep 1