Title : Increased expression of cdc2 inhibits transport function of RLIP76 and promotes apoptosis.

Pub. Date : 2009 Oct 8

PMID : 19375851






3 Functional Relationships(s)
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Protein Name
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1 Both doxorubicin (DOX) and dinitro-phenyl S-glutathione (DNP-SG) transport were inhibited by cdc2 in a concentration dependent manner. Doxorubicin cyclin dependent kinase 1 Homo sapiens
2 Both doxorubicin (DOX) and dinitro-phenyl S-glutathione (DNP-SG) transport were inhibited by cdc2 in a concentration dependent manner. Doxorubicin cyclin dependent kinase 1 Homo sapiens
3 Liposomal delivery of cdc2 to H358 cells caused apoptosis, resulted in an increased intracellular doxorubicin-accumulation and decreased rate of efflux from the cells. Doxorubicin cyclin dependent kinase 1 Homo sapiens