Title : Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.

Pub. Date : 2004 May

PMID : 15141020






1 Functional Relationships(s)
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Protein Name
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1 Adriamycin inhibits histone H3(Ser10) phosphorylation through inhibitory phosphorylation of CDC2 at low doses and down-regulation of cyclin B1 at high doses. Doxorubicin cyclin dependent kinase 1 Homo sapiens