| 101 |
15769597 | The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism. | 2005 May 15 |
2 |
| 102 |
15786723 | Prevention of cataract by pyruvate in experimentally diabetic mice. | 2005 Jan |
1 |
| 103 |
15814847 | Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options. | 2005 May |
4 |
| 104 |
16026266 | Aldose reductase in diabetic microvascular complications. | 2005 Jun |
1 |
| 105 |
16166459 | Morphological and functional changes in the diabetic peripheral nerve: using diagnostic ultrasound and neurosensory testing to select candidates for nerve decompression. | 2005 Sep-Oct |
1 |
| 106 |
16356117 | Regulation of the human taurine transporter by oxidative stress in retinal pigment epithelial cells stably transformed to overexpress aldose reductase. | 2005 Nov-Dec |
2 |
| 107 |
15095003 | Strategies for the design of inhibitors of aldose reductase, an enzyme showing pronounced induced-fit adaptations. | 2004 Apr |
1 |
| 108 |
15250036 | Thiamine and benfotiamine prevent increased apoptosis in endothelial cells and pericytes cultured in high glucose. | 2004 Jul-Aug |
1 |
| 109 |
15539002 | Aldose reductase inhibition in the treatment of diabetic neuropathy: where are we in 2004? | 2004 Dec |
1 |
| 110 |
12490536 | Aldose reductase mediates cytotoxic signals of hyperglycemia and TNF-alpha in human lens epithelial cells. | 2003 Feb |
2 |
| 111 |
12527382 | Protein kinase C-dependent phosphorylation and mitochondrial translocation of aldose reductase. | 2003 Jan 16 |
2 |
| 112 |
12604218 | Up-regulation of aldose reductase by the substrate, methylglyoxal. | 2003 Feb 1 |
6 |
| 113 |
12606529 | The response of antioxidant genes to hyperglycemia is abnormal in patients with type 1 diabetes and diabetic nephropathy. | 2003 Mar |
1 |
| 114 |
12615520 | Polymorphisms of sorbitol dehydrogenase (SDH) gene and susceptibility to diabetic retinopathy. | 2003 Apr |
2 |
| 115 |
12639759 | The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes. | 2003 Apr |
1 |
| 116 |
12732097 | Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism. | 2003 Aug 1 |
1 |
| 117 |
12824263 | High glucose-induced tyrosine nitration in endothelial cells: role of eNOS uncoupling and aldose reductase activation. | 2003 Jul |
4 |
| 118 |
12855766 | Electrostatic complementarity in an aldose reductase complex from ultra-high-resolution crystallography and first-principles calculations. | 2003 Jul 22 |
1 |
| 119 |
12871133 | Recent studies of aldose reductase enzyme inhibition for diabetic complications. | 2003 Aug |
4 |
| 120 |
12871134 | Aldose reductase inhibitors from the nature. | 2003 Aug |
1 |
| 121 |
12962626 | X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. | 2003 Sep |
1 |
| 122 |
11772943 | Aldose reductase activation is a key component of myocardial response to ischemia. | 2002 Feb |
1 |
| 123 |
11796181 | (AC)(n) polymorphism of aldose reductase gene and diabetic microvascular complications in type 2 diabetes mellitus. | 2002 Feb |
1 |
| 124 |
11942168 | [Hyperglycemia and vascular damage role of oxidative stress]. | 2002 Mar |
1 |
| 125 |
12034372 | Drug-resistant human lung cancer cells are more sensitive to selenium cytotoxicity. Effects on thioredoxin reductase and glutathione reductase. | 2002 May 15 |
1 |
| 126 |
12200074 | Mechanisms of inhibitory activity of the aldose reductase inhibitor, epalrestat, on high glucose-mediated endothelial injury: neutrophil-endothelial cell adhesion and surface expression of endothelial adhesion molecules. | 2002 Sep-Oct |
1 |
| 127 |
12394272 | Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic drugs and involves activation of extracellular signal-regulated kinases. | 2002 Sep |
1 |
| 128 |
11306074 | Metabolism of the 2-oxoaldehyde methylglyoxal by aldose reductase and by glyoxalase-I: roles for glutathione in both enzymes and implications for diabetic complications. | 2001 Jan 30 |
1 |
| 129 |
11422753 | Aldose reductase expression is induced by hyperglycemia in diabetic nephropathy. | 2001 Jul |
1 |
| 130 |
12164386 | Aldose reductase inhibitors. | 2001 Dec |
1 |
| 131 |
12363257 | Discoveries in research on diabetic keratopathy. | 2001 Nov |
1 |
| 132 |
10733904 | Purification, identification, and characterization of an osmotic response element binding protein. | 2000 Apr 2 |
2 |
| 133 |
10818070 | Aldose reductase inhibitor improves insulin-mediated glucose uptake and prevents migration of human coronary artery smooth muscle cells induced by high glucose. | 2000 May |
4 |
| 134 |
10997687 | The missing link: a single unifying mechanism for diabetic complications. | 2000 Sep |
1 |
| 135 |
9890881 | Structural and kinetic determinants of aldehyde reduction by aldose reductase. | 1999 Jan 5 |
1 |
| 136 |
10199583 | Inhibition of aldose reductase in human erythrocytes by vitamin C. | 1999 Jan |
2 |
| 137 |
10229296 | Effect of aldose reductase inhibitors on glucose-induced changes in sorbitol and myo-inositol metabolism in human neutrophils. | 1999 Jan |
5 |
| 138 |
10400634 | Osmotic response element enhancer activity. Regulation through p38 kinase and mitogen-activated extracellular signal-regulated kinase kinase. | 1999 Jul 16 |
1 |
| 139 |
10443578 | Glucose-induced oxidative stress and programmed cell death in diabetic neuropathy. | 1999 Jun 30 |
1 |
| 140 |
10516137 | Downregulation of the human taurine transporter by glucose in cultured retinal pigment epithelial cells. | 1999 Oct |
6 |
| 141 |
10559643 | Decreased degradation of collagen and fibronectin following exposure of proximal cells to glucose. | 1999 Sep-Dec |
1 |
| 142 |
10789192 | [The role of cellular glucose transporters in pathogenesis of diabetic nephropathy]. | 1999 |
1 |
| 143 |
11139842 | Aldose reductase inhibitors: therapeutic implications for diabetic complications. | 1999 Dec |
2 |
| 144 |
9541179 | An aldose reductase inhibitor prevents glucose-induced increase in transforming growth factor-beta and protein kinase C activity in cultured mesangial cells. | 1998 Mar |
2 |
| 145 |
9583077 | [Aldose reductase in the polyol pathway: a potential target for the therapeutic intervention of diabetic complications]. | 1998 Mar |
2 |
| 146 |
9678260 | The inhibitory effect of benzodiazepine derivatives on the bovine lens aldose reductase enzyme. | 1998 Jun |
1 |
| 147 |
9681469 | Depletion of phospholipid arachidonoyl-containing molecular species in a human Schwann cell line grown in elevated glucose and their restoration by an aldose reductase inhibitor. | 1998 Aug |
1 |
| 148 |
9000650 | Restoration of nitric oxide production by aldose reductase inhibitor in human endothelial cells cultured in high-glucose medium. | 1997 |
3 |
| 149 |
9000706 | Polymorphism in the 5'-end of the aldose reductase gene is strongly associated with the development of diabetic nephropathy in type I diabetes. | 1997 Feb |
2 |
| 150 |
9029308 | Sensitive, selective gas chromatographic-mass spectrometric analysis with trifluoroacetyl derivatives and a stable isotope for studying tissue sorbitol-producing activity. | 1997 Jan 10 |
1 |