Title : Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism.

Pub. Date : 2003 Aug 1

PMID : 12732097






1 Functional Relationships(s)
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1 Glucose was a poor inhibitor ( K (i)=80 mM) of retinal reductase activity of human AR, whereas tolrestat, a classical AKR inhibitor used pharmacologically to treat diabetes, inhibited retinal reduction by human AR and HSI AR. Glucose aldo-keto reductase family 1 member B Homo sapiens