| 51 |
23901876 | Discovery of new selective human aldose reductase inhibitors through virtual screening multiple binding pocket conformations. | 2013 Sep 23 |
1 |
| 52 |
24019949 | A new approach to control the enigmatic activity of aldose reductase. | 2013 |
1 |
| 53 |
24353900 | Thioredoxin Interacting Protein (TXNIP) and Pathogenesis of Diabetic Retinopathy. | 2013 Aug 5 |
1 |
| 54 |
21637955 | Aldose reductase regulates TNF-α-induced inducible nitric oxide synthase expression in human mesangial cells. | 2012 Feb |
2 |
| 55 |
22249747 | Pharmacophore modeling, molecular docking, and molecular dynamics simulation approaches for identifying new lead compounds for inhibiting aldose reductase 2. | 2012 Jul |
2 |
| 56 |
22283786 | A potential therapeutic role for aldose reductase inhibitors in the treatment of endotoxin-related inflammatory diseases. | 2012 Mar |
2 |
| 57 |
22565168 | High glucose levels induce inhibition of Na,K-ATPase via stimulation of aldose reductase, formation of microtubules and formation of an acetylated tubulin/Na,K-ATPase complex. | 2012 Aug |
3 |
| 58 |
22582044 | Aldose reductase, oxidative stress, and diabetic mellitus. | 2012 |
5 |
| 59 |
22911800 | Aldolase B knockdown prevents high glucose-induced methylglyoxal overproduction and cellular dysfunction in endothelial cells. | 2012 |
2 |
| 60 |
22951256 | Regulation of transforming growth factor β1-dependent aldose reductase expression by the Nrf2 signal pathway in human mesangial cells. | 2012 Oct |
2 |
| 61 |
21319207 | Synthesis and biological evaluation of 2'-oxo-2,3-dihydro-3'H- spiro[chromene-4,5'-[1,3]oxazolidin]-3'yl]acetic acid derivatives as aldose reductase inhibitors. | 2011 Jun |
1 |
| 62 |
21354119 | Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders. | 2011 May 30 |
2 |
| 63 |
19778627 | Aldose reductase: a novel therapeutic target for inflammatory pathologies. | 2010 Jan |
2 |
| 64 |
19821053 | Role of aldose reductase in the high glucose induced expression of fibronectin in human mesangial cells. | 2010 Jul |
1 |
| 65 |
20218967 | 3D-QSAR Studies on a Series of 5-Arylidine-2, 4-Thiazolidinediones as Aldose Reductase Inhibitors: A Self-Organizing Molecular Field Analysis Approach. | 2010 Mar 11 |
2 |
| 66 |
20308528 | Aldose reductase regulates vascular smooth muscle cell proliferation by modulating G1/S phase transition of cell cycle. | 2010 May |
2 |
| 67 |
20402658 | 3D-QSAR studies on a series of 5-arylidine-2, 4-thiazolidinediones as aldose reductase inhibitors: a self-organizing molecular field analysis approach. | 2010 Jan |
2 |
| 68 |
20466987 | Aldose reductase and cardiovascular diseases, creating human-like diabetic complications in an experimental model. | 2010 May 14 |
1 |
| 69 |
20573996 | Cardiac contractile dysfunction during acute hyperglycemia due to impairment of SERCA by polyol pathway-mediated oxidative stress. | 2010 Sep |
1 |
| 70 |
20642441 | Understanding the role of aldose reductase in ocular inflammation. | 2010 Aug |
1 |
| 71 |
19199934 | Aldose reductase enzyme and its implication to major health problems of the 21(st) century. | 2009 |
1 |
| 72 |
19301313 | Structure-based optimization of aldose reductase inhibitors originating from virtual screening. | 2009 May |
2 |
| 73 |
19397838 | Transcription factors in the pathogenesis of diabetic nephropathy. | 2009 Apr 28 |
1 |
| 74 |
19480738 | Atorvastatin reduces the expression of aldo-keto reductases in HUVEC and PTEC. A new approach to influence the polyol pathway. | 2009 Jun 1 |
2 |
| 75 |
19522700 | Aldo-keto reductase family 1 member B1 inhibitors: old drugs with new perspectives. | 2009 Nov |
3 |
| 76 |
19602579 | Oxidative stress and dysregulation of the taurine transporter in high-glucose-exposed human Schwann cells: implications for pathogenesis of diabetic neuropathy. | 2009 Sep |
1 |
| 77 |
19682763 | Aldose reductase inhibitor counteracts the attenuated adhesion of human corneal epithelial cells induced by high glucose through modulation of MMP-10 expression. | 2009 Oct |
2 |
| 78 |
19702120 | [New aspects about the impact of oxidative stress on development of chronic diabetic complications]. | 2009 |
1 |
| 79 |
18325349 | High glucose induction of DNA-binding activity of the transcription factor NFkappaB in patients with diabetic nephropathy. | 2008 May |
4 |
| 80 |
18325492 | Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers. | 2008 Apr 28 |
2 |
| 81 |
18362110 | Role of the polyol pathway in high glucose-induced apoptosis of retinal pericytes and proliferation of endothelial cells. | 2008 Jul |
3 |
| 82 |
18451330 | Upregulation of aldose reductase during foam cell formation as possible link among diabetes, hyperlipidemia, and atherosclerosis. | 2008 Jun |
1 |
| 83 |
18537622 | From a dull enzyme to something else: facts and perspectives regarding aldose reductase. | 2008 |
1 |
| 84 |
20151040 | Phospho-Site-Specific Antibody Microarray to Study the State of Protein Phosphorylation in the Retina. | 2008 Aug 13 |
3 |
| 85 |
17202704 | Exploring structural feature of aldose-reductase inhibition by 5-[[2-(omega-carboxyalkoxy)aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives employing Fujita-Ban and Hansch approach. | 2007 Jan |
2 |
| 86 |
17368668 | Structural and thermodynamic study on aldose reductase: nitro-substituted inhibitors with strong enthalpic binding contribution. | 2007 May 4 |
1 |
| 87 |
17497245 | Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites. | 2007 Aug |
3 |
| 88 |
17508915 | Pyridine nucleotide redox abnormalities in diabetes. | 2007 Jul |
2 |
| 89 |
17584970 | Aldose reductase-regulated tumor necrosis factor-alpha production is essential for high glucose-induced vascular smooth muscle cell growth. | 2007 Sep |
1 |
| 90 |
17905306 | Tracing changes in protonation: a prerequisite to factorize thermodynamic data of inhibitor binding to aldose reductase. | 2007 Nov 9 |
1 |
| 91 |
17943821 | Aldose reductase inhibitors for the treatment of diabetic polyneuropathy. | 2007 Oct 17 |
1 |
| 92 |
16278369 | Polyol pathway in human epididymis and semen. | 2006 Mar-Apr |
1 |
| 93 |
16452468 | Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose. | 2006 Apr 7 |
2 |
| 94 |
16596633 | Study of the polyol pathway in the porcine epididymis. | 2006 Jul |
1 |
| 95 |
16624439 | The role of polyol pathway in high glucose-induced endothelial cell damages. | 2006 Sep |
2 |
| 96 |
16631166 | Aldose reductase prevents aldehyde toxicity in cultured human lens epithelial cells. | 2006 Aug |
2 |
| 97 |
16631535 | Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells. | 2006 Apr 15 |
1 |
| 98 |
16639747 | Structure of a glutathione conjugate bound to the active site of aldose reductase. | 2006 Jul 1 |
1 |
| 99 |
16644704 | Elevated activity of transcription factor nuclear factor of activated T-cells 5 (NFAT5) and diabetic nephropathy. | 2006 May |
3 |
| 100 |
15637423 | C-106T polymorphism in promoter of aldose reductase gene is a risk factor for diabetic nephropathy in type 2 diabetes patients with poor glycaemic control. | 2005 |
2 |