Title : [Hyperglycemia and vascular damage role of oxidative stress].

Pub. Date : 2002 Mar

PMID : 11942168






1 Functional Relationships(s)
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1 High glucose levels are associated with the non-enzymatic glycation of both extra- and intracellular proteins, the accumulation of sorbitol via the aldose-reductase pathway, the activation of protein kinase C isoforms, and the reduced bioavailability of nitric oxide. Glucose aldo-keto reductase family 1 member B Homo sapiens