Cisplatin

AKT serine/threonine kinase 1 ; Homo sapiens







518 Article(s)
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51 33859780 Zoledronic Acid Enhanced the Antitumor Effect of Cisplatin on Orthotopic Osteosarcoma by ROS-PI3K/AKT Signaling and Attenuated Osteolysis. 2021 3
52 33908630 Cyanidin-3-O-glucoside and cisplatin inhibit proliferation and downregulate the PI3K/AKT/mTOR pathway in cervical cancer cells. 2021 Jun 1
53 33960434 Antitumor and antimigration effects of Salvia clandestina L. extract on osteosarcoma cells. 2021 Sep 1
54 34017375 Kinesin family member 2A promotes cancer cell viability, mobility, stemness, and chemoresistance to cisplatin by activating the PI3K/AKT/VEGF signaling pathway in non-small cell lung cancer. 2021 1
55 34026767 Retraction: Parthenolide Augments the Chemosensitivity of Non-small-Cell Lung Cancer to Cisplatin via the PI3K/AKT Signaling Pathway. 2021 1
56 34046349 Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway. 2021 2
57 34068624 Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism. 2021 May 10 1
58 34077013 Apatinib strengthens the anti-tumor effect of cisplatin in thyroid carcinoma through downregulating VEGFR2. 2021 Mar-Apr 4
59 34077027 Tormentic acid induces anticancer effects in cisplatin-resistant human cervical cancer cells mediated via cell cycle arrest, ROS production, and targeting mTOR/PI3K/AKT signalling pathway. 2021 Mar-Apr 2
60 34077275 Resveratrol upregulates miR-455-5p to antagonize cisplatin ototoxicity via modulating the PTEN-PI3K-AKT axis. 2021 Jun 1
61 34096570 MiR-27a-3p enhances the cisplatin sensitivity in hepatocellular carcinoma cells through inhibiting PI3K/Akt pathway. 2021 Dec 22 2
62 34230143 Inhibition of AKT Enhances the Sensitivity of NSCLC Cells to Metformin. 2021 Jul 1
63 34261004 Cisplatin's potential for type 2 diabetes repositioning by inhibiting CDKN1A, FAS, and SESN1. 2021 Aug 1
64 34266345 MicroRNA-25-3p promotes cisplatin resistance in Non-small-cell lung carcinoma (NSCLC) through adjusting PTEN/PI3K/AKT route. 2021 Dec 1
65 34277602 NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway. 2021 2
66 34277781 A novel peptide promotes human trophoblast proliferation and migration through PI3K/Akt/mTOR signaling pathway. 2021 Jun 1
67 34313895 Silencing of ATG4D suppressed proliferation and enhanced cisplatin-induced apoptosis in hepatocellular carcinoma through Akt/Caspase-3 pathway. 2021 Nov 1
68 34427099 HDAC3-mediated lncRNA-LOC101928316 contributes to cisplatin resistance in gastric cancer via activating the PI3K-Akt-mTOR pathway. 2021 Sep 1
69 34475767 Daam1 Overexpression Promotes Gastric Cancer Progression and Regulates ERK and AKT Signaling Pathways. 2021 1
70 34486197 HGF/c-MET pathway contributes to cisplatin-mediated PD-L1 expression in hepatocellular carcinoma. 2021 Dec 3
71 34542810 Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway. 2021 Nov 2
72 34585447 Zeylenone synergizes with cisplatin in osteosarcoma by enhancing DNA damage, apoptosis, and necrosis via the Hsp90/AKT/GSK3β and Fanconi anaemia pathway. 2021 Oct 2
73 34598710 TTK is a potential therapeutic target for cisplatin-resistant ovarian cancer. 2021 Oct 2 1
74 34638339 Heat Shock Protein 27, a Novel Downstream Target of Collagen Type XI alpha 1, Synergizes with Fatty Acid Oxidation to Confer Cisplatin Resistance in Ovarian Cancer Cells. 2021 Sep 28 1
75 34888594 [Insight into the role of IGF2BP1 in drug resistant mechanism of oral squamous cell carcinoma]. 2021 Oct 2
76 34901018 Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways. 2021 1
77 34915755 A nano based approach to alleviate cisplatin induced nephrotoxicity. 2021 Jan-Dec 1
78 34953496 Cordycepin augments the chemosensitivity of osteosarcoma to cisplatin by activating AMPK and suppressing the AKT signaling pathway. 2021 Dec 25 1
79 34977076 Lanthanum Chloride Sensitizes Cisplatin Resistance of Ovarian Cancer Cells via PI3K/Akt Pathway. 2021 1
80 31267531 microRNA-10b confers cisplatin resistance by activating AKT/mTOR/P70S6K signaling via targeting PPARγ in esophageal cancer. 2020 Feb 3
81 31558183 Overexpression of the Long Noncoding RNA FOXD2-AS1 Promotes Cisplatin Resistance in Esophageal Squamous Cell Carcinoma Through the miR-195/Akt/mTOR Axis. 2020 Feb 7 3
82 31630149 Nitroglycerin Enhances Cisplatin-Induced Cytotoxicity via AKT Inactivation and Thymidylate Synthase Downregulation in Human Lung Cancer Cells. 2020 1
83 31648572 Radiosensitizing Potential of Curcumin in Different Cancer Models. 2020 1
84 31742349 Protective effects of human umbilical cord mesenchymal stem cell-derived conditioned medium on ovarian damage. 2020 Jun 11 1
85 31843707 Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy. 2020 Mar 1
86 31875760 Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway. 2020 Dec 1
87 31885317 The long noncoding RNA CRAL reverses cisplatin resistance via the miR-505/CYLD/AKT axis in human gastric cancer cells. 2020 Nov 4
88 31897216 AFAP1-AS1 induces cisplatin resistance in non-small cell lung cancer through PI3K/AKT pathway. 2020 Jan 1
89 31905343 Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter. 2020 Jan 6 1
90 31913198 miR-21 modulates cisplatin resistance of gastric cancer cells by inhibiting autophagy via the PI3K/Akt/mTOR pathway. 2020 Apr 3
91 31983246 Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling. 2020 Nov 1
92 32021259 miR-1269b Drives Cisplatin Resistance of Human Non-Small Cell Lung Cancer via Modulating the PTEN/PI3K/AKT Signaling Pathway. 2020 2
93 32027070 MicroRNA-31 weakens cisplatin resistance of medulloblastoma cells via NF-κB and PI3K/AKT pathways. 2020 Sep 1
94 32064052 Correction: The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer. 2020 Jan 28 1
95 32104214 Ghrelin inhibits cisplatin-induced MDA-MB-231 breast cancer cell apoptosis via PI3K/Akt/mTOR signaling. 2020 Mar 3
96 32165307 TRIM59 knockdown blocks cisplatin resistance in A549/DDP cells through regulating PTEN/AKT/HK2. 2020 Jul 15 1
97 32186774 miR‑10a increases the cisplatin resistance of lung adenocarcinoma circulating tumor cells via targeting PIK3CA in the PI3K/Akt pathway. 2020 Jun 3
98 32222530 Metformin enhances the sensitivity of colorectal cancer cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway. 2020 Jun 30 3
99 32277616 Tormentic acid induces anticancer effects in cisplatin-resistant human cervical cancer cells mediated via cell cycle arrest, ROS production, and targeting mTOR/PI3K/AKT signalling pathway. 2020 Jan-Feb 2
100 32308421 miR-34c Targets MET to Improve the Anti-Tumor Effect of Cisplatin on Ovarian Cancer. 2020 1