Title : A novel peptide promotes human trophoblast proliferation and migration through PI3K/Akt/mTOR signaling pathway.

Pub. Date : 2021 Jun

PMID : 34277781






1 Functional Relationships(s)
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1 The experiment shows that ROPPIP can up-regulate the expression levels of MMP2, Ki67, and Bcl2 in HTR-8/Svneo cells, down-regulate the expression of caspase-3, promote the proliferation and migration of HTR-8/Svneo cells and inhibit the apoptosis induced by cisplatin, the activation of the phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathway may be associated with the function of ROPPIP. Cisplatin AKT serine/threonine kinase 1 Homo sapiens