Title : Zeylenone synergizes with cisplatin in osteosarcoma by enhancing DNA damage, apoptosis, and necrosis via the Hsp90/AKT/GSK3β and Fanconi anaemia pathway.

Pub. Date : 2021 Oct

PMID : 34585447






2 Functional Relationships(s)
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1 Zeylenone synergizes with cisplatin in osteosarcoma by enhancing DNA damage, apoptosis, and necrosis via the Hsp90/AKT/GSK3beta and Fanconi anaemia pathway. Cisplatin AKT serine/threonine kinase 1 Homo sapiens
2 Thus, the Hsp90/AKT/GSK3beta and FA pathway are the key to the synergism between zey and cisplatin. Cisplatin AKT serine/threonine kinase 1 Homo sapiens