Pub. Date : 2021 Mar-Apr
PMID : 34077013
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The protein levels of p-VEGFR2, VEGFR2, p-Akt, Akt, p-mTOR and mTOR in TPC-1 cells influenced by the treatment of Apatinib combined with cisplatin were examined by Western blot. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | The protein levels of p-VEGFR2, VEGFR2, p-Akt, Akt, p-mTOR and mTOR in TPC-1 cells influenced by the treatment of Apatinib combined with cisplatin were examined by Western blot. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Apatinib treatment strengthened the anti-tumor influence of cisplatin on TPC-1 cells through downregulating p-VEGFR2, p-Akt and p-mTOR. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | CONCLUSIONS: Apatinib strengthens the anti-tumor influence of cisplatin in thyroid carcinoma through VEGFR2-Akt-mTOR pathway. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |