| 1 |
34637881 | Antiproliferative effects of metformin in cellular models of pheochromocytoma. | 2022 Jan 1 |
1 |
| 2 |
34714980 | Metformin protects against abdominal aortic aneurysm by Atg7-induced autophagy. | 2022 Jan |
1 |
| 3 |
35044756 | Synergistic Effects of Combined Anthocyanin and Metformin Treatment for Hyperglycemia In Vitro and In Vivo. | 2022 Feb 2 |
1 |
| 4 |
35125086 | Nimbolide, a Neem Limonoid, Inhibits Angiogenesis in Breast Cancer by Abrogating Aldose Reductase Mediated IGF-1/PI3K/Akt Signalling. | 2022 |
1 |
| 5 |
35236827 | Metformin suppresses the growth of colorectal cancer by targeting INHBA to inhibit TGF-β/PI3K/AKT signaling transduction. | 2022 Mar 2 |
3 |
| 6 |
35326689 | In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D3, and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the PI3K/Akt/PTEN/mTOR Network. | 2022 Mar 17 |
1 |
| 7 |
35350904 | Plantamajoside promotes metformin-induced apoptosis, autophagy and proliferation arrest of liver cancer cells via suppressing Akt/GSK3β signaling. | 2022 Jan-Dec |
3 |
| 8 |
35387349 | Metformin Promotes Differentiation and Attenuates H2O2-Induced Oxidative Damage of Osteoblasts via the PI3K/AKT/Nrf2/HO-1 Pathway. | 2022 |
5 |
| 9 |
35413055 | Sera from women with different metabolic and menopause states differentially regulate cell viability and Akt activation in a breast cancer in-vitro model. | 2022 |
1 |
| 10 |
35496297 | Metformin and Thymoquinone Synergistically Inhibit Proliferation of Imatinib-Resistant Human Leukemic Cells. | 2022 |
1 |
| 11 |
35528246 | Therapeutic Effect of P-Cymene on Lipid Profile, Liver Enzyme, and Akt/Mtor Pathway in Streptozotocin-Induced Diabetes Mellitus in Wistar Rats. | 2022 |
2 |
| 12 |
35550195 | Metformin-induced downregulation of c-Met is a determinant of sensitivity in MDA-MB-468 breast cancer cells. | 2022 Jul 12 |
1 |
| 13 |
35610639 | Metformin exerts an antitumor effect by inhibiting bladder cancer cell migration and growth, and promoting apoptosis through the PI3K/AKT/mTOR pathway. | 2022 May 24 |
2 |
| 14 |
33236135 | Metformin induces apoptosis and inhibits migration by activating the AMPK/p53 axis and suppressing PI3K/AKT signaling in human cervical cancer cells. | 2021 Jan |
2 |
| 15 |
33524789 | The effects of metformin on autophagy. | 2021 May |
2 |
| 16 |
33690729 | Changes in protein expression due to metformin treatment and hyperinsulinemia in a human endometrial cancer cell line. | 2021 |
1 |
| 17 |
33762564 | Retracted: Anticancer Activity of Metformin, an Antidiabetic Drug, Against Ovarian Cancer Cells Involves Inhibition of Cysteine-Rich 61 (Cyr61)/Akt/Mammalian Target of Rapamycin (mTOR) Signaling Pathway. | 2021 Mar 25 |
2 |
| 18 |
33927970 | Role of insulin receptor substance-1 modulating PI3K/Akt insulin signaling pathway in Alzheimer's disease. | 2021 Apr |
1 |
| 19 |
34004440 | Metformin prevents BAFF activation of Erk1/2 from B-cell proliferation and survival by impeding mTOR-PTEN/Akt signaling pathway. | 2021 Jul |
5 |
| 20 |
34078517 | Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism. | 2021 Jun 1 |
9 |
| 21 |
34197898 | Metformin attenuates rotenone-induced oxidative stress and mitochondrial damage via the AKT/Nrf2 pathway. | 2021 Sep |
2 |
| 22 |
34230143 | Inhibition of AKT Enhances the Sensitivity of NSCLC Cells to Metformin. | 2021 Jul |
8 |
| 23 |
34335983 | CCDC65 as a new potential tumor suppressor induced by metformin inhibits activation of AKT1 via ubiquitination of ENO1 in gastric cancer. | 2021 |
3 |
| 24 |
34440224 | Clinical Implication of Metformin in Relation to Diabetes Mellitus and Ovarian Cancer. | 2021 Aug 16 |
1 |
| 25 |
34480296 | Repurposing new drug candidates and identifying crucial molecules underlying PCOS Pathogenesis Based On Bioinformatics Analysis. | 2021 Dec |
1 |
| 26 |
34642298 | Metformin alleviates inflammation through suppressing FASN-dependent palmitoylation of Akt. | 2021 Oct 12 |
4 |
| 27 |
34745769 | Metformin promotes anticancer activity of NK cells in a p38 MAPK dependent manner. | 2021 |
1 |
| 28 |
34790753 | Metformin alleviates bevacizumab-induced vascular endothelial injury by up-regulating GDF15 and activating the PI3K/AKT/FOXO/PPARγ signaling pathway. | 2021 Oct |
2 |
| 29 |
34895136 | Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way. | 2021 Dec 11 |
6 |
| 30 |
31715142 | Metformin promotes osteogenic differentiation and protects against oxidative stress-induced damage in periodontal ligament stem cells via activation of the Akt/Nrf2 signaling pathway. | 2020 Jan 15 |
2 |
| 31 |
31789625 | Metformin mediated microRNA-7 upregulation inhibits growth, migration, and invasion of non-small cell lung cancer A549 cells. | 2020 Apr |
2 |
| 32 |
31830378 | Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway. | 2020 Feb |
3 |
| 33 |
31864213 | iTRAQ-based quantitative proteomic analysis of the inhibition of cervical cancer cell invasion and migration by metformin. | 2020 Mar |
1 |
| 34 |
31894313 | Metformin alleviates endometrial hyperplasia through the UCA1/miR‑144/TGF‑β1/AKT signaling pathway. | 2020 Feb |
3 |
| 35 |
31902918 | Metformin Suppresses LPS-Induced Inflammatory Responses in Macrophage and Ameliorates Allergic Contact Dermatitis in Mice via Autophagy. | 2020 |
1 |
| 36 |
31998447 | Metformin Promotes Axon Regeneration after Spinal Cord Injury through Inhibiting Oxidative Stress and Stabilizing Microtubule. | 2020 |
3 |
| 37 |
32222530 | Metformin enhances the sensitivity of colorectal cancer cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway. | 2020 Jun 30 |
3 |
| 38 |
32229782 | Metformin as an Alternative Radiosensitizing Agent to 5-Fluorouracil During Neoadjuvant Treatment for Rectal Cancer. | 2020 Jul |
1 |
| 39 |
32460900 | Elevated de novo protein synthesis in FMRP-deficient human neurons and its correction by metformin treatment. | 2020 May 27 |
1 |
| 40 |
32495867 | Metformin reduces pancreatic cancer cell proliferation and increases apoptosis through MTOR signaling pathway and its dose-effect relationship. | 2020 May |
1 |
| 41 |
32627027 | Metformin inhibits TGF‑β1‑induced epithelial‑mesenchymal transition and liver metastasis of pancreatic cancer cells. | 2020 Jul |
5 |
| 42 |
32631421 | Metformin inhibits cervical cancer cell proliferation by modulating PI3K/Akt-induced major histocompatibility complex class I-related chain A gene expression. | 2020 Jul 6 |
3 |
| 43 |
32734128 | Antitumor Activity of Combination Therapy with Metformin and Trametinib in Non-Small Cell Lung Cancer Cells. | 2020 Jun |
4 |
| 44 |
32748870 | Metformin and Everolimus: A Promising Combination for Neuroendocrine Tumors Treatment. | 2020 Aug 2 |
2 |
| 45 |
32825834 | Neoadjuvant metformin added to conventional chemotherapy synergizes anti-proliferative effects in ovarian cancer. | 2020 Aug 21 |
2 |
| 46 |
32861747 | Upregulation of Akt/Raptor signaling is associated with rapamycin resistance of breast cancer cells. | 2020 Oct 1 |
2 |
| 47 |
32934724 | Therapeutic effect of metformin in the treatment of endometrial cancer. | 2020 Nov |
1 |
| 48 |
32945402 | Metformin promotes cell proliferation and osteogenesis under high glucose condition by regulating the ROS‑AKT‑mTOR axis. | 2020 Oct |
5 |
| 49 |
32970287 | Metformin downregulates miR223 expression in insulin-resistant 3T3L1 cells and human diabetic adipose tissue. | 2020 Dec |
3 |
| 50 |
32974191 | Matrix Stiffness-Upregulated MicroRNA-17-5p Attenuates the Intervention Effects of Metformin on HCC Invasion and Metastasis by Targeting the PTEN/PI3K/Akt Pathway. | 2020 |
5 |