| 1 |
32189555 | The expression and activity of thymidine kinase 1 and deoxycytidine kinase are modulated by hydrogen peroxide and nucleoside analogs. | 2020 |
2 |
| 2 |
30539536 | Engineered Thymidine-Active Deoxycytidine Kinase for Bystander Killing of Malignant Cells. | 2019 |
2 |
| 3 |
29393406 | Deoxycytidine kinase participates in the regulation of radiation-induced autophagy and apoptosis in breast cancer cells. | 2018 Mar |
1 |
| 4 |
29695239 | Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity. | 2018 Apr 25 |
1 |
| 5 |
29715301 | TMSOTf assisted synthesis of 2'-deoxy-2'-[18F]fluoro-β-D-arabinofuranosylcytosine ([18F]FAC). | 2018 |
2 |
| 6 |
26620371 | A crucial role for ATR in the regulation of deoxycytidine kinase activity. | 2016 Jan 15 |
1 |
| 7 |
24419380 | Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules. | 2014 Jan |
3 |
| 8 |
24462681 | Protein phosphatase 2A regulates deoxycytidine kinase activity via Ser-74 dephosphorylation. | 2014 Mar 3 |
1 |
| 9 |
22902741 | Homogeneous assay for real-time and simultaneous detection of thymidine kinase 1 and deoxycytidine kinase activities. | 2013 Jan 15 |
1 |
| 10 |
24066967 | New insights into the synergism of nucleoside analogs with radiotherapy. | 2013 Sep 26 |
4 |
| 11 |
22850745 | Deoxycytidine kinase regulates the G2/M checkpoint through interaction with cyclin-dependent kinase 1 in response to DNA damage. | 2012 Oct |
1 |
| 12 |
22927829 | Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation. | 2012 Aug |
1 |
| 13 |
23148236 | Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress. | 2012 Nov 19 |
1 |
| 14 |
23230188 | Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment. | 2012 Dec |
1 |
| 15 |
21127859 | Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway. | 2011 Apr |
1 |
| 16 |
21351740 | Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release. | 2011 Apr 12 |
2 |
| 17 |
21362344 | Relationship between single nucleotide polymorphisms in the deoxycytidine kinase gene and chemosensitivity of gemcitabine in six pancreatic cancer cell lines. | 2011 Feb |
1 |
| 18 |
19959816 | Novel potent inhibitors of deoxycytidine kinase identified and compared by multiple assays. | 2010 Jan |
1 |
| 19 |
20080663 | Requirement for deoxycytidine kinase in T and B lymphocyte development. | 2010 Mar 23 |
2 |
| 20 |
20614893 | Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues . | 2010 Aug 10 |
1 |
| 21 |
20637175 | Casein kinase 1delta activates human recombinant deoxycytidine kinase by Ser-74 phosphorylation, but is not involved in the in vivo regulation of its activity. | 2010 Oct 1 |
1 |
| 22 |
20684612 | The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): implications for the development of dCK-activated acyclic guanine analogues. | 2010 Aug 12 |
4 |
| 23 |
20957432 | Optimization and evaluation of electroporation delivery of siRNA in the human leukemic CEM cell line. | 2010 Dec |
2 |
| 24 |
19159229 | Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase. | 2009 Feb 17 |
1 |
| 25 |
18361501 | Systematic exploration of active site mutations on human deoxycytidine kinase substrate specificity. | 2008 Apr 22 |
1 |
| 26 |
18487070 | 2'-deoxy-4'-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants. | 2008 |
1 |
| 27 |
18600530 | RNAi depletion of deoxycytidine and deoxyguanosine kinase in human leukemic CEM cells. | 2008 Jun |
2 |
| 28 |
18974616 | Twenty novel genetic variations and haplotype structures of the DCK gene encoding human deoxycytidine kinase (dCK). | 2008 |
1 |
| 29 |
17158155 | Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase. | 2007 |
1 |
| 30 |
17350163 | Positive regulation of deoxycytidine kinase activity by phosphorylation of Ser-74 in B-cell chronic lymphocytic leukaemia lymphocytes. | 2007 Aug 8 |
2 |
| 31 |
18084067 | Structures of human deoxycytidine kinase product complexes. | 2007 Dec |
2 |
| 32 |
16421443 | The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation. | 2006 Feb |
1 |
| 33 |
16463058 | Gemcitabine resistance due to deoxycytidine kinase deficiency can be reverted by fruitfly deoxynucleoside kinase, DmdNK, in human uterine sarcoma cells. | 2006 Oct |
1 |
| 34 |
16533034 | Fluorescence energy transfer studies of human deoxycytidine kinase: role of cysteine 185 in the conformational changes that occur upon substrate binding. | 2006 Mar 21 |
1 |
| 35 |
16936229 | A new mechanism of methotrexate action revealed by target screening with affinity beads. | 2006 Nov |
1 |
| 36 |
15752710 | Activation of deoxycytidine kinase by deoxyadenosine: implications in deoxyadenosine-mediated cytotoxicity. | 2005 Apr 1 |
1 |
| 37 |
15764852 | Thymidine kinase and deoxycytidine kinase activity in mononuclear cells from antiretroviral-naive HIV-infected patients. | 2005 Mar 25 |
1 |
| 38 |
15876539 | Docking simulation with a purine nucleoside specific homology model of deoxycytidine kinase, a target enzyme for anticancer and antiviral therapy. | 2005 Jul 1 |
1 |
| 39 |
15104248 | Activation of deoxycytidine kinase in lymphocytes is calcium dependent and involves a conformational change detectable by native immunostaining. | 2004 Mar 1 |
1 |
| 40 |
15183121 | Activation of deoxycytidine kinase by protein kinase inhibitors and okadaic acid in leukemic cells. | 2004 Jul 1 |
4 |
| 41 |
15520873 | [Special function of deoxycytidine kinase (dCK) in the activation of chemotherapeutic nucleoside analogs and in the inhibition of cell proliferation]. | 2004 |
2 |
| 42 |
15571259 | New evidences for a regulation of deoxycytidine kinase activity by reversible phosphorylation. | 2004 Oct |
1 |
| 43 |
12504799 | Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance. | 2003 Jan 15 |
1 |
| 44 |
12566083 | Selective activation of deoxycytidine kinase by thymidine-5'-thiosulphate and release by deoxycytidine in human lymphocytes. | 2003 Feb 15 |
1 |
| 45 |
12604712 | Phosphorylation of 4'-thio-beta-D-arabinofuranosylcytosine and its analogs by human deoxycytidine kinase. | 2003 Mar |
1 |
| 46 |
12808445 | Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. | 2003 Jul |
1 |
| 47 |
12925971 | Sensitization of ara-C-resistant lymphoma cells by a pronucleotide analogue. | 2003 Oct 20 |
1 |
| 48 |
11896543 | Real-time quantitative PCR assays for deoxycytidine kinase, deoxyguanosine kinase and 5'-nucleotidase mRNA measurement in cell lines and in patients with leukemia. | 2002 Mar |
1 |
| 49 |
11992640 | Modifications of deoxycytidine kinase and deaminase activities by docosahexaenoic acid in normal and transformed rat fibroblasts. | 2002 Feb 15 |
1 |
| 50 |
12054684 | Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-beta-D-arabinofuranosylguanine cytotoxicity. | 2002 May 24 |
2 |