Pub. Date : 2012 Aug
PMID : 22927829
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | As a proof of concept we created a library of mutants of the human deoxycytidine kinase (dCK) gene, involved in the activation of nucleoside analogues used in cancer treatment, with the aim of isolating a variant sensitizing cancer cells to the chemotherapy compound Gemcitabine, to be used in gene therapy for anti-cancer approaches or as a poorly immunogenic negative selection marker for cell transplantation approaches. | Nucleosides | Calcium/calmodulin-dependent protein kinase II | Drosophila melanogaster |