Title : Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues .

Pub. Date : 2010 Aug 10

PMID : 20614893






1 Functional Relationships(s)
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1 This hypothesis is supported by the observation that mutations that enlarge the active site cavity in proximity to the nucleoside 5-position endow dCK with the ability to phosphorylate thymidine. Nucleosides Calcium/calmodulin-dependent protein kinase II Drosophila melanogaster