Title : Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase.

Pub. Date : 2007

PMID : 17158155






1 Functional Relationships(s)
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1 The capability of dCK to phosphorylate both D- and L-nucleosides and nucleoside analogs derives from structural properties of both the enzyme and the substrates themselves. Nucleosides Calcium/calmodulin-dependent protein kinase II Drosophila melanogaster