Title : Requirement for deoxycytidine kinase in T and B lymphocyte development.

Pub. Date : 2010 Mar 23

PMID : 20080663






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 dCK phosphorylates and therefore activates nucleoside analog prodrugs frequently used in cancer, autoimmunity, and viral infections. Nucleosides Calcium/calmodulin-dependent protein kinase II Drosophila melanogaster
2 The severe impact of dCK inactivation on lymphopoiesis was unexpected given that nucleoside salvage has been thought to play a limited, "fine-tuning" role in regulating deoxyribonucleotide triphosphate pools produced by the de novo pathway. Nucleosides Calcium/calmodulin-dependent protein kinase II Drosophila melanogaster