Title : Selective activation of deoxycytidine kinase by thymidine-5'-thiosulphate and release by deoxycytidine in human lymphocytes.

Pub. Date : 2003 Feb 15

PMID : 12566083






1 Functional Relationships(s)
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1 Deoxycytidine kinase (dCK) catalyses the rate-limiting step of the salvage of three natural deoxyribonucleosides as well as several therapeutic nucleoside analogues, which in turn can enhance its enzymatic activity [Biochem Pharmacol 56 (1998) 1175], improving the efficacy of the cytostatic therapy. Nucleosides Calcium/calmodulin-dependent protein kinase II Drosophila melanogaster