| 1 |
35167695 | It takes two to Tango: IGF-I and TSH Receptors in Thyroid Eye Disease. | 2022 Feb 15 |
1 |
| 2 |
33991522 | The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1. | 2021 Jan-Jun |
1 |
| 3 |
32252327 | New Insights from IGF-IR Stimulating Activity Analyses: Pathological Considerations. | 2020 Apr 2 |
1 |
| 4 |
32849999 | Glutamate Attenuates the Survival Property of IGFR through NR2B Containing N-Methyl-D-aspartate Receptors in Cortical Neurons. | 2020 |
1 |
| 5 |
31594955 | Structural basis of the activation of type 1 insulin-like growth factor receptor. | 2019 Oct 8 |
1 |
| 6 |
32422022 | Hyperactivated Insulin Signaling Cascade in Human Glioblastoma Cells. | 2019 |
2 |
| 7 |
30697189 | Klotho Gene and Protein in Human Placentas According to Birth Weight and Gestational Age. | 2018 |
1 |
| 8 |
28126338 | USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination. | 2017 Mar 11 |
1 |
| 9 |
28460125 | How Protein Kinase A Activates Canonical Tyrosine Kinase Signaling Pathways To Promote Granulosa Cell Differentiation. | 2017 Jul 1 |
1 |
| 10 |
26702053 | Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation. | 2016 Feb 26 |
2 |
| 11 |
25694432 | The interaction of protein-tyrosine phosphatase α (PTPα) and RACK1 protein enables insulin-like growth factor 1 (IGF-1)-stimulated Abl-dependent and -independent tyrosine phosphorylation of PTPα. | 2015 Apr 10 |
4 |
| 12 |
25840417 | Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses. | 2015 Jun 30 |
1 |
| 13 |
24186145 | Plasma amino acid profiles are associated with biomarkers of breast cancer risk in premenopausal Japanese women. | 2014 Feb |
1 |
| 14 |
23460259 | GRK2 negatively regulates IGF-1R signaling pathway and cyclins' expression in HepG2 cells. | 2013 Sep |
1 |
| 15 |
23478262 | The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation. | 2013 May |
2 |
| 16 |
23481042 | Platelet-derived growth factor negatively regulates the insulin-like growth factor signaling pathway through the coordinated action of phosphatidylinositol 3-kinase and protein kinase C beta I. | 2013 Jun |
1 |
| 17 |
24216110 | Functional roles of BCAR3 in the signaling pathways of insulin leading to DNA synthesis, membrane ruffling and GLUT4 translocation. | 2013 Nov 29 |
2 |
| 18 |
24648957 | Type II cGMP-dependent protein kinase inhibits activation of key members of the RTK family in gastric cancer cells. | 2013 May |
3 |
| 19 |
22227580 | Phosphatidylinositol 3-kinase and protein kinase D1 specifically cooperate to negatively regulate the insulin-like growth factor signaling pathway. | 2012 Feb |
2 |
| 20 |
22269172 | Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells. | 2012 Jan 23 |
1 |
| 21 |
22309212 | Novel missense mutation in the IGF-I receptor L2 domain results in intrauterine and postnatal growth retardation. | 2012 Aug |
1 |
| 22 |
22447628 | Chemerin inhibits IGF-1-induced progesterone and estradiol secretion in human granulosa cells. | 2012 Jun |
2 |
| 23 |
22738911 | Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases. | 2012 Aug 15 |
1 |
| 24 |
22767591 | Phosphatidylinositol 3-kinase (PI3K) activity bound to insulin-like growth factor-I (IGF-I) receptor, which is continuously sustained by IGF-I stimulation, is required for IGF-I-induced cell proliferation. | 2012 Aug 24 |
2 |
| 25 |
22912850 | Identification of the amino acids 300-600 of IRS-2 as 14-3-3 binding region with the importance of IGF-1/insulin-regulated phosphorylation of Ser-573. | 2012 |
1 |
| 26 |
23650573 | IGF-1 receptor is down-regulated by sunitinib induces MDM2-dependent ubiquitination. | 2012 |
1 |
| 27 |
20962017 | Clinical and functional characteristics of a novel heterozygous mutation of the IGF1R gene and IGF1R haploinsufficiency due to terminal 15q26.2->qter deletion in patients with intrauterine growth retardation and postnatal catch-up growth failure. | 2011 Jan |
1 |
| 28 |
21454706 | Differential signaling by adaptor molecules LRP1 and ShcA regulates adipogenesis by the insulin-like growth factor-1 receptor. | 2011 May 13 |
1 |
| 29 |
21457754 | Specific targeting of insulin-like growth factor 1 receptor signaling in human estrogen dependent breast cancer cell by a novel tyrosine-based benzoxazepine derivative. | 2011 May 16 |
1 |
| 30 |
20044479 | Selective disruption of insulin-like growth factor-1 (IGF-1) signaling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death. | 2010 Feb 26 |
1 |
| 31 |
20144629 | Homologous posttranscriptional regulation of insulin-like growth factor-I receptor level via glycogen synthase kinase-3beta and mammalian target of rapamycin in adrenal chromaffin cells: effect on tau phosphorylation. | 2010 Jun |
1 |
| 32 |
20185348 | IGF-I stimulates reactive oxygen species (ROS) production and inhibits insulin-dependent glucose uptake via ROS in 3T3-L1 adipocytes. | 2010 Jun |
2 |
| 33 |
20363874 | AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation. | 2010 Jun |
1 |
| 34 |
20515953 | A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo. | 2010 Jun |
1 |
| 35 |
19164446 | Interruption of growth hormone signaling via SHC and ERK in 3T3-F442A preadipocytes upon knockdown of insulin receptor substrate-1. | 2009 Apr |
1 |
| 36 |
19217170 | Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotective and cytotoxic bilirubin. | 2009 Mar |
2 |
| 37 |
19420001 | Protein tyrosine phosphatase-alpha complexes with the IGF-I receptor and undergoes IGF-I-stimulated tyrosine phosphorylation that mediates cell migration. | 2009 Jul |
7 |
| 38 |
19423701 | Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase. | 2009 Jul 24 |
1 |
| 39 |
19596798 | Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes. | 2009 Aug 1 |
1 |
| 40 |
19762915 | Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways. | 2009 Nov 13 |
2 |
| 41 |
17607710 | Expression of the human beta3 integrin subunit in mouse smooth muscle cells enhances IGF-I-stimulated signaling and proliferation. | 2008 Feb |
1 |
| 42 |
18023142 | Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells. | 2008 Feb |
1 |
| 43 |
18056704 | mTORC1 signaling can regulate growth factor activation of p44/42 mitogen-activated protein kinases through protein phosphatase 2A. | 2008 Feb 1 |
3 |
| 44 |
18079194 | Abnormalities of insulin-like growth factor-I signaling and impaired cell proliferation in osteoblasts from subjects with osteoporosis. | 2008 Mar |
2 |
| 45 |
18292237 | Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I. | 2008 May |
1 |
| 46 |
18403642 | Prolactin does not require insulin-like growth factor intermediates but synergizes with insulin-like growth factor I in human breast cancer cells. | 2008 Apr |
1 |
| 47 |
18502759 | Alanine scanning of a putative receptor binding surface of insulin-like growth factor-I. | 2008 Jul 25 |
9 |
| 48 |
18567578 | Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and beta1 integrin and for tumor cell proliferation and migration. | 2008 Aug 22 |
2 |
| 49 |
18606861 | p66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 membrane recruitment. | 2008 Sep |
2 |
| 50 |
17216192 | A proteomic approach to the investigation of early events involved in vascular smooth muscle cell activation. | 2007 Apr |
1 |