Title : Identification of the amino acids 300-600 of IRS-2 as 14-3-3 binding region with the importance of IGF-1/insulin-regulated phosphorylation of Ser-573.

Pub. Date : 2012

PMID : 22912850






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Phosphorylation of insulin receptor substrate (IRS)-2 on tyrosine residues is a key event in IGF-1/insulin signaling and leads to activation of the PI 3-kinase and the Ras/MAPK pathway. Tyrosine insulin like growth factor 1 Homo sapiens