Title : Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and beta1 integrin and for tumor cell proliferation and migration.

Pub. Date : 2008 Aug 22

PMID : 18567578






2 Functional Relationships(s)
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1 Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and beta1 integrin and for tumor cell proliferation and migration. Tyrosine insulin like growth factor 1 Homo sapiens
2 Taken together, the data demonstrate that Tyr-302 in RACK1 is required for interaction with PP2A and beta1 integrin, for regulation of PP2A activity, and for IGF-I-mediated cell migration and proliferation. Tyrosine insulin like growth factor 1 Homo sapiens