Title : IGF-I stimulates reactive oxygen species (ROS) production and inhibits insulin-dependent glucose uptake via ROS in 3T3-L1 adipocytes.

Pub. Date : 2010 Jun

PMID : 20185348






2 Functional Relationships(s)
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Protein Name
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1 Serine phosphorylation of IRS-1 was strongly induced and the insulin-dependent tyrosine phosphorylation of IRS-1 was suppressed by preincubating the adipocytes with IGF-I. Tyrosine insulin like growth factor 1 Homo sapiens
2 Further, NAC restored these changes induced by IGF-I on both serine and tyrosine phosphorylation of IRS-1. Tyrosine insulin like growth factor 1 Homo sapiens