Pub. Date : 2000 Nov
PMID : 11129289
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Paclitaxel was chosen for combination therapy in the preclinical study reported here due to its extensive use as a first-line therapy in ovarian cancer, its synergy with SCH58500 in preclinical cancer models, and its activation of p53-independent apoptosis, which might result in a "lowered threshold" for tumor cell death. | Paclitaxel | tumor protein p53 | Homo sapiens |