| 1 |
34562089 | The Protective Effect of Natural Compounds on Doxorubicin-Induced Cardiotoxicity via Nicotinamide Adenine Dinucleotide Phosphate Oxidase Inhibition. | 2022 Mar 3 |
1 |
| 2 |
34130091 | Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. | 2021 Aug |
3 |
| 3 |
34919052 | NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis. | 2021 Dec 17 |
3 |
| 4 |
31812668 | Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells. | 2020 Jan 15 |
1 |
| 5 |
32093281 | Knockdown of TFAM in Tumor Cells Retarded Autophagic Flux through Regulating p53 Acetylation and PISD Expression. | 2020 Feb 20 |
1 |
| 6 |
32371497 | p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators. | 2020 May 5 |
8 |
| 7 |
33040724 | Regulation of Thiamine (Vitamin B1)-Dependent Metabolism in Mammals by p53. | 2020 Jul |
1 |
| 8 |
30050056 | TSPYL2 is a novel regulator of SIRT1 and p300 activity in response to DNA damage. | 2019 May |
3 |
| 9 |
30778219 | NAD+ metabolism governs the proinflammatory senescence-associated secretome. | 2019 Mar |
1 |
| 10 |
29307819 | Absence of REV3L promotes p53-regulated cancer cell metabolism in cisplatin-treated lung carcinoma cells. | 2018 Jan 29 |
1 |
| 11 |
29476819 | Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. | 2018 May |
2 |
| 12 |
30518708 | SIRT1 knockdown up-regulates p53 and p21/Cip1 expression in renal adenocarcinoma cells but not in normal renal-derived cells in a deacetylase-independent manner. | 2018 |
1 |
| 13 |
28845527 | Extracellular NAMPT/visfatin causes p53 deacetylation via NAD production and SIRT1 activation in breast cancer cells. | 2017 Aug |
2 |
| 14 |
26712469 | Concurrent acetylation of FoxO1/3a and p53 due to sirtuins inhibition elicit Bim/PUMA mediated mitochondrial dysfunction and apoptosis in berberine-treated HepG2 cells. | 2016 Jan 15 |
1 |
| 15 |
27608947 | NAMPT inhibition synergizes with NQO1-targeting agents in inducing apoptotic cell death in non-small cell lung cancer cells. | 2016 Aug |
1 |
| 16 |
27816507 | NAD+ salvage pathway in cancer metabolism and therapy. | 2016 Dec |
1 |
| 17 |
25971446 | Oxidative DNA damage induced by metabolites of chloramphenicol, an antibiotic drug. | 2015 |
1 |
| 18 |
24548601 | SIRT1 modulates miRNA processing defects in p53-mutated human keratinocytes. | 2014 May |
2 |
| 19 |
24552824 | The NAD+ synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target. | 2014 |
5 |
| 20 |
24819061 | Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways. | 2014 May 12 |
8 |
| 21 |
25033286 | Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation. | 2014 |
1 |
| 22 |
23798621 | Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. | 2013 Jun |
1 |
| 23 |
24009628 | SIRT1 Expression Is Associated with Good Prognosis in Colorectal Cancer. | 2013 Aug |
1 |
| 24 |
24512730 | The sirtuin inhibitor tenovin-6 upregulates death receptor 5 and enhances cytotoxic effects of 5-fluorouracil and oxaliplatin in colon cancer cells. | 2013 |
1 |
| 25 |
21979946 | Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53. | 2012 Jan 15 |
2 |
| 26 |
22735644 | DBC1 phosphorylation by ATM/ATR inhibits SIRT1 deacetylase in response to DNA damage. | 2012 Oct |
1 |
| 27 |
21245319 | Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1). | 2011 Feb 1 |
4 |
| 28 |
21807113 | Sirt1 deacetylates c-Myc and promotes c-Myc/Max association. | 2011 Nov |
1 |
| 29 |
22180829 | The role of SIRT1 in tumorigenesis. | 2011 |
1 |
| 30 |
20471503 | SIRT1 and p53, effect on cancer, senescence and beyond. | 2010 Aug |
1 |
| 31 |
20631301 | Sirtuin 1 regulation of developmental genes during differentiation of stem cells. | 2010 Aug 3 |
1 |
| 32 |
20975832 | SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53. | 2010 Oct 21 |
1 |
| 33 |
19188449 | hSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damage. | 2009 Apr |
1 |
| 34 |
19682970 | A fluorometric assay of SIRT1 deacetylation activity through quantification of nicotinamide adenine dinucleotide. | 2009 Dec 15 |
1 |
| 35 |
19833096 | Red wine decreases asymmetric dimethylarginine via SIRT1 induction in human endothelial cells. | 2009 Dec 18 |
1 |
| 36 |
17454128 | Photosensitized DNA damage induced by NADH: site specificity and mechanism. | 2007 Apr |
1 |
| 37 |
17595514 | H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion. | 2007 |
1 |
| 38 |
17806102 | Function of the SIRT1 protein deacetylase in cancer. | 2007 Nov |
1 |
| 39 |
16618762 | Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. | 2006 Apr 15 |
1 |
| 40 |
16082197 | p53 proteasomal degradation: poly-ubiquitination is not the whole story. | 2005 Aug |
1 |
| 41 |
15509798 | NAD+ modulates p53 DNA binding specificity and function. | 2004 Nov |
10 |
| 42 |
12867035 | Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription. | 2003 Jul 15 |
1 |
| 43 |
12918120 | X-ray induced L02 cells damage rescued by new anti-oxidant NADH. | 2003 Aug |
2 |
| 44 |
12390773 | [Effect of NADH against liver cell line L02 apoptosis induced by UVB irradiation]. | 2002 Mar |
2 |
| 45 |
11672522 | Negative control of p53 by Sir2alpha promotes cell survival under stress. | 2001 Oct 19 |
1 |
| 46 |
11672523 | hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. | 2001 Oct 19 |
1 |
| 47 |
10945628 | Role of poly(ADP-ribosyl)ation in the killing of chronic lymphocytic leukemia cells by purine analogues. | 2000 Aug 1 |
1 |
| 48 |
10331640 | Mapping the role of NAD metabolism in prevention and treatment of carcinogenesis. | 1999 Mar |
3 |
| 49 |
10334203 | Oxidative damage to cellular and isolated DNA by metabolites of a fungicide ortho-phenylphenol. | 1999 May |
1 |
| 50 |
10697561 | Effect of extracellular NADH on human tumor cell proliferation. | 1999 Nov-Dec |
1 |