Title : Oxidative damage to cellular and isolated DNA by metabolites of a fungicide ortho-phenylphenol.

Pub. Date : 1999 May

PMID : 10334203






1 Functional Relationships(s)
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1 Using 32P-5"-end-labeled DNA fragments obtained from human p53 tumor suppressor gene and c-Ha-ras-1 protooncogene, we showed that PBQ plus NADH, and also PHQ, induced DNA damage frequently at thymine residues, in the presence of Cu(II). NAD tumor protein p53 Homo sapiens