Title : SIRT1 and p53, effect on cancer, senescence and beyond.

Pub. Date : 2010 Aug

PMID : 20471503






1 Functional Relationships(s)
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Protein Name
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1 NAD(+)-dependent Class III histone deacetylase SIRT1 is a multiple function protein critically involved in stress responses, cellular metabolism and aging through deacetylating a variety of substrates including p53, forkhead-box transcription factors, PGC-1alpha, NF-kappaB, Ku70 and histones. NAD tumor protein p53 Homo sapiens