Title : X-ray induced L02 cells damage rescued by new anti-oxidant NADH.

Pub. Date : 2003 Aug

PMID : 12918120






2 Functional Relationships(s)
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1 NADH could not only eliminate the apoptosis induced by X-ray irradiation, but also up-regulate expression of bcl-2 protein and down-regulate expression of p53, bax, fas and fasL proteins (P<0.05). NAD tumor protein p53 Homo sapiens
2 CONCLUSION: NADH has marked anti-radiation effect, its mechanism may be associated with up-regulation of bcl-2 expression and down-regulation of p53, bax fas and fasL expression, as well as decline of intracellular ROS. NAD tumor protein p53 Homo sapiens