Title : Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes.

Pub. Date : 2006 Apr 15

PMID : 16618762






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SIRT1 and other NAD-dependent deacetylases have been implicated in control of cellular responses to stress and in tumorigenesis through deacetylation of important regulatory proteins, including p53 and the BCL6 oncoprotein. NAD tumor protein p53 Homo sapiens