arsenite

tumor protein p53 ; Homo sapiens







39 Article(s)
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1 34425169 Time-dependent genomic response in primary human uroepithelial cells exposed to arsenite for up to 60 days. 2021 Sep 1
2 31931413 N6-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation. 2020 Apr 2
3 32265434 Selective degradation of IKKα by autophagy is essential for arsenite-induced cancer cell apoptosis. 2020 Apr 7 1
4 32315827 Pigment epithelium-derived factor (PEDF) ameliorates arsenic-induced vascular endothelial dysfunction in rats and toxicity in endothelial EA.hy926 cells. 2020 Jul 1
5 32373892 Linc-ROR promotes arsenite-transformed keratinocyte proliferation by inhibiting P53 activity. 2020 Jun 24 6
6 33097607 Autophagic feedback-mediated degradation of IKKα requires CHK1- and p300/CBP-dependent acetylation of p53. 2020 Nov 16 1
7 30177839 Transcriptional repression of IKKβ by p53 in arsenite-induced GADD45α accumulation and apoptosis. 2019 Jan 3
8 28785074 Low dose arsenite confers resistance to UV induced apoptosis via p53-MDM2 pathway in ketatinocytes. 2017 Aug 7 5
9 23396362 NF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1. 2014 Feb 20 1
10 24499675 Arsenite induces premature senescence via p53/p21 pathway as a result of DNA damage in human malignant glioblastoma cells. 2014 Oct 5
11 22130551 Aquaporins mediate the chemoresistance of human melanoma cells to arsenite. 2012 Feb 1
12 22260869 Arsenite-induced apoptosis of human neuroblastoma cells requires p53 but occurs independently of c-Jun. 2012 Mar 29 11
13 22366412 DNA-PKcs-mediated stabilization of p53 by JNK2 is involved in arsenite-induced DNA damage and apoptosis in human embryo lung fibroblast cells. 2012 May 5 3
14 22447124 Blockade of p53 by HIF-2α, but not HIF-1α, is involved in arsenite-induced malignant transformation of human bronchial epithelial cells. 2012 Jun 2
15 22551203 Effects of arsenic exposure on DNA methylation in cord blood samples from newborn babies and in a human lymphoblast cell line. 2012 May 2 1
16 22706169 Opposed arsenite-mediated regulation of p53-survivin is involved in neoplastic transformation, DNA damage, or apoptosis in human keratinocytes. 2012 Oct 28 4
17 21292642 Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b. 2011 May 3
18 19931552 Arsenite promotes centrosome abnormalities under a p53 compromised status induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). 2010 Feb 15 3
19 20000476 Suppression of p53 and p21CIP1/WAF1 reduces arsenite-induced aneuploidy. 2010 Feb 15 2
20 20036271 Arsenite induced poly(ADP-ribosyl)ation of tumor suppressor P53 in human skin keratinocytes as a possible mechanism for carcinogenesis associated with arsenic exposure. 2010 Mar 15 5
21 20199942 mot-2-Mediated cross talk between nuclear factor-B and p53 is involved in arsenite-induced tumorigenesis of human embryo lung fibroblast cells. 2010 Jul 6
22 20375080 The repressive effect of NF-kappaB on p53 by mot-2 is involved in human keratinocyte transformation induced by low levels of arsenite. 2010 Jul 5
23 19470404 Arsenite enhances the benzo[a]pyrene diol epoxide (BPDE)-induced mutagenesis with no marked effect on repair of BPDE-DNA adducts in human lung cells. 2009 Aug 3
24 17849503 GSK3 promotes arsenite-induced apoptosis via facilitation of mitochondria disruption. 2008 May 1
25 18201741 The contribution of c-Jun N-terminal kinase activation and subsequent Bcl-2 phosphorylation to apoptosis induction in human B-cells is dependent on the mode of action of specific stresses. 2008 Apr 1 1
26 18504176 [Construction and expression of different mutants of human p53 and their effects on arsenite-induced cell apoptosis]. 2008 May 5
27 19010883 Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation. 2008 Nov 15 1
28 17906315 Arsenic salt-induced DNA damage and expression of mutant p53 and COX-2 proteins in SV-40 immortalized human uroepithelial cells. 2007 Nov 3
29 17945324 Arsenic promotes centrosome abnormalities and cell colony formation in p53 compromised human lung cells. 2007 Dec 1 2
30 16338954 Depletion of securin increases arsenite-induced chromosome instability and apoptosis via a p53-independent pathway. 2006 Mar 6
31 16614167 p53 suppression of arsenite-induced mitotic catastrophe is mediated by p21CIP1/WAF1. 2006 Jul 7
32 16645841 ATM/ATR-related checkpoint signals mediate arsenite-induced G2/M arrest in primary aortic endothelial cells. 2006 Dec 2
33 16966095 Exit from arsenite-induced mitotic arrest is p53 dependent. 2006 Sep 12
34 11813266 Sodium arsenite suppresses human papillomavirus-16 E6 gene and enhances apoptosis in E6-transfected human lymphoblastoid cells. 2002 2
35 11406180 Effects of arsenite on p53, p21 and cyclin D expression in normal human fibroblasts -- a possible mechanism for arsenite's comutagenicity. 2001 Jul 1 5
36 11429707 Contrasting roles of NF-kappaB and JNK in arsenite-induced p53-independent expression of GADD45alpha. 2001 Jun 14 3
37 11489357 Both hypomethylation and hypermethylation of DNA associated with arsenite exposure in cultures of human cells identified by methylation-sensitive arbitrarily-primed PCR. 2001 Jul 6 1
38 11103796 Arsenite induces p53 accumulation through an ATM-dependent pathway in human fibroblasts. 2000 Nov 15 8
39 10491313 Arsenic disrupts cellular levels of p53 and mdm2: a potential mechanism of carcinogenesis. 1999 Sep 24 2