Pub. Date : 2006 Mar
PMID : 16338954
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenite raised the levels of phospho-p53 (serine-15) and p53 (DO-1) proteins in both the securin-wild-type and -null cells. | arsenite | tumor protein p53 | Homo sapiens |
| 2 | Arsenite raised the levels of phospho-p53 (serine-15) and p53 (DO-1) proteins in both the securin-wild-type and -null cells. | arsenite | tumor protein p53 | Homo sapiens |
| 3 | The p53-functional cells were more susceptible than the p53-mutational cells to arsenite on the cytotoxicity and apoptosis. | arsenite | tumor protein p53 | Homo sapiens |
| 4 | The p53-functional cells were more susceptible than the p53-mutational cells to arsenite on the cytotoxicity and apoptosis. | arsenite | tumor protein p53 | Homo sapiens |
| 5 | Besides, arsenite decreased the levels of securin proteins to a similar degree in both the p53-functional and -mutational cells. | arsenite | tumor protein p53 | Homo sapiens |
| 6 | Together, it is the first time to demonstrate that the inhibition of securin expression induced by arsenite increases the chromosomal instability and apoptosis via a p53-independent pathway. | arsenite | tumor protein p53 | Homo sapiens |