Arsenic

tumor protein p53 ; Homo sapiens







75 Article(s)
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1 34798143 Up-regulation of PUMA caused the activation of p53 phosphorylation and acetylation, enhancing the interaction between PUMA and Bcl-X and mediating arsenic-induced apoptosis. 2022 Jan 1 1
2 35188613 Arsenic concentration in topsoil of central Chile is associated with aberrant methylation of P53 gene in human blood cells: a cross-sectional study. 2022 Feb 21 1
3 32816178 Arsenic exposure increased expression of HOTAIR and LincRNA-p21 in vivo and vitro. 2021 Jan 1
4 33357454 Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site. 2021 Feb 8 3
5 33501840 Role of inhibiting Chk1-p53 pathway in hepatotoxicity caused by chronic arsenic exposure from coal-burning. 2021 Jul 3
6 33561393 Arsenic and an Old Place: Rescuing p53 Mutants in Cancer. 2021 Feb 8 2
7 34047175 A Pin1/PML/P53 axis activated by retinoic acid in NPM-1c acute myeloid leukemia. 2021 Dec 1 1
8 34959015 Arsenic causes mitochondrial biogenesis obstacles by inhibiting the AMPK/PGC-1α signaling pathway and also induces apoptosis and dysregulated mitophagy in the duck liver. 2021 Dec 24 1
9 32315827 Pigment epithelium-derived factor (PEDF) ameliorates arsenic-induced vascular endothelial dysfunction in rats and toxicity in endothelial EA.hy926 cells. 2020 Jul 1
10 33254717 The role of Hipk2-p53 pathways in arsenic-induced autistic behaviors: A translational study from rats to humans. 2020 Dec 4
11 29319823 Differentially Expressed mRNA Targets of Differentially Expressed miRNAs Predict Changes in the TP53 Axis and Carcinogenesis-Related Pathways in Human Keratinocytes Chronically Exposed to Arsenic. 2018 Apr 1 1
12 27851896 Corrigendum to "Low doses of arsenic, via perturbing p53, promotes tumorigenesis" [Toxicol. Appl. Pharmacol. (2016) 98-104]. 2017 Jan 1 1
13 28337271 Effects of long term low- and high-dose sodium arsenite exposure in human transitional cells. 2017 1
14 26440706 p53-based strategy to reduce hematological toxicity of chemotherapy: A proof of principle study. 2016 Jan 1
15 26772154 LincRNAs and base modifications of p53 induced by arsenic methylation in workers. 2016 Feb 25 5
16 26953705 Arsenic projects in SE Asia. 2016 Mar 1
17 27425828 Low doses of arsenic, via perturbing p53, promotes tumorigenesis. 2016 Sep 1 3
18 24665044 Arsenic exposure through drinking water leads to senescence and alteration of telomere length in humans: A case-control study in West Bengal, India. 2015 Sep 1
19 25199682 Epigenetic mechanisms underlying arsenic-associated lung carcinogenesis. 2015 Nov 3
20 26091798 Human bronchial epithelial BEAS-2B cells, an appropriate in vitro model to study heavy metals induced carcinogenesis. 2015 Sep 15 6
21 26148435 Arsenic-induced S phase cell cycle lengthening is associated with ROS generation, p53 signaling and CDC25A expression. 2015 Aug 5 9
22 26292025 Low-dose arsenic-mediated metabolic shift is associated with activation of Polo-like kinase 1 (Plk1). 2015 2
23 26606645 Arsenic cardiotoxicity: An overview. 2015 Nov 1
24 27122327 [Changes in mRNA expression of p53 and related downstream genes in peripheral blood lymphocytes in workers occupationally exposed to arsenic]. 2015 Dec 6
25 23524579 Low-dose arsenic induces chemotherapy protection via p53/NF-κB-mediated metabolic regulation. 2014 Mar 13 3
26 24391088 A low-dose arsenic-induced p53 protein-mediated metabolic mechanism of radiotherapy protection. 2014 Feb 21 2
27 23174854 Low concentration of arsenic-induced aberrant mitosis in keratinocytes through E2F1 transcriptionally regulated Aurora-A. 2013 Mar 1
28 23549458 CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure. 2013 Jan 14 1
29 24255851 Human GMDS gene fragment hypermethylation in chronic high level of arsenic exposure with and without arsenic induced cancer. 2013 1
30 22509835 Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes. 2012 May 2
31 22551203 Effects of arsenic exposure on DNA methylation in cord blood samples from newborn babies and in a human lymphoblast cell line. 2012 May 2 2
32 21194611 Toxicity of depleted uranium complexes is independent of p53 activity. 2011 Feb 1
33 21454520 Mutant p53 protein is targeted by arsenic for degradation and plays a role in arsenic-mediated growth suppression. 2011 May 20 10
34 21550362 Metabolites of arsenic and increased DNA damage of p53 gene in arsenic plant workers. 2011 Jul 1 2
35 21554949 Arsenic-induced oxidative stress and its reversibility. 2011 Jul 15 1
36 21756780 [Relationship between the methylation and mutation of p53 gene and endemic arsenism caused by coal-burning]. 2011 May 4
37 21914522 Chronic arsenic toxicity: studies in West Bengal, India. 2011 Sep 2
38 21982800 The polymorphisms of P53 codon 72 and MDM2 SNP309 and renal cell carcinoma risk in a low arsenic exposure area. 2011 Dec 15 4
39 20036271 Arsenite induced poly(ADP-ribosyl)ation of tumor suppressor P53 in human skin keratinocytes as a possible mechanism for carcinogenesis associated with arsenic exposure. 2010 Mar 15 1
40 20123963 Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences. 2010 Apr 1
41 19513507 The overexpression of multidrug resistance-associated proteins and gankyrin contribute to arsenic trioxide resistance in liver and gastric cancer cells. 2009 Jul 3
42 18085531 Attenuation of DNA damage-induced p53 expression by arsenic: a possible mechanism for arsenic co-carcinogenesis. 2008 Jul 5
43 18249029 Arsenic-induced health effects and genetic damage in keratotic individuals: involvement of p53 arginine variant and chromosomal aberrations in arsenic susceptibility. 2008 Jul-Aug 2
44 18621066 Increased damage of exon 5 of p53 gene in workers from an arsenic plant. 2008 Aug 25 2
45 18640142 Polymorphisms in cell cycle regulatory genes, urinary arsenic profile and urothelial carcinoma. 2008 Oct 15 1
46 19010883 Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation. 2008 Nov 15 2
47 19013355 Metals and apoptosis: recent developments. 2008 1
48 16973168 Effects of arsenic exposure and genetic polymorphisms of p53, glutathione S-transferase M1, T1, and P1 on the risk of carotid atherosclerosis in Taiwan. 2007 Jun 1
49 17567589 p53 response to arsenic exposure in epithelial cells: protein kinase B/Akt involvement. 2007 Sep 4
50 17718444 [Real-time PCR used to detect p53 gene damage in workers exposed to arsenic]. 2007 Jul 9