Title : Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

Pub. Date : 2010 Apr

PMID : 20123963






1 Functional Relationships(s)
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1 To elucidate the direct phosphorylation of p53 at Ser46 by ATM, an ATM mutant (ATM-AS) sensitive to ATP analogues was engineered. Arsenic tumor protein p53 Homo sapiens