Title : Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation.

Pub. Date : 2008 Nov 15

PMID : 19010883






2 Functional Relationships(s)
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1 Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation. Arsenic tumor protein p53 Homo sapiens
2 Together, our data suggests that arsenic compounds predispose cells to malignant transformation by up-regulation of Hdm2 and subsequent p53 inactivation. Arsenic tumor protein p53 Homo sapiens