Pub. Date : 2015
PMID : 26292025
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | It was recently shown that low-dose arsenic leads to a metabolic shift from mitochondrial respiration to aerobic glycolysis via inactivation of tumor suppressor p53 and activation of NF-kappaB. | Arsenic | tumor protein p53 | Homo sapiens |
2 | However, how inactivation of p53, activation of NF-kappaB, and metabolic change are coordinated in response to low-dose arsenic exposure is still not completely understood. | Arsenic | tumor protein p53 | Homo sapiens |