Title : Metformin Synergistically Enhanced the Antitumor Activity of Celecoxib in Human Non-Small Cell Lung Cancer Cells.

Pub. Date : 2020

PMID : 32792943






1 Functional Relationships(s)
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1 Further study of the underlying mechanism revealed that the two drugs in combination caused ROS aggregation in NSCLC cells, leading to DNA double-strand breaks and increased expression of the tumor suppressor factor p53. ros tumor protein p53 Homo sapiens