Title : MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1.

Pub. Date : 2019 Feb 18

PMID : 30778058






1 Functional Relationships(s)
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1 Mechanistically, miR-135 accumulates specifically in response to glutamine deprivation and requires ROS-dependent activation of mutant p53, which directly promotes miR-135 expression. ros tumor protein p53 Homo sapiens