Pub. Date : 2022 Mar 15
PMID : 35074406
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | HIWI2 induces G2/M cell cycle arrest and apoptosis in human fibrosarcoma via the ROS/DNA damage/p53 axis. | ros | tumor protein p53 | Homo sapiens |
| 2 | SIGNIFICANCE: These results are the first to show that HIWI2 acts as a tumor suppressor in fibrosarcoma by modulating the ROS/DNA damage/p53 pathway. | ros | tumor protein p53 | Homo sapiens |